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What are the actions of Bromazepam?
| Q: |
I write for to ask yours about some informations on the pharmacology and pharmacokynetics of Bromazepam (benzodiazepinic drug). I seek by this information on the Erowid pages but I can't find nothing I want. |
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| A: |
Bromazepam is a short to medium acting benzodiazepine similar to alprazolam (Xanax) most often used in the treatment of anxiety. It is a Central Nervous System (CNS) depressant. It is considered to have a half-life of between 8 and 30 hours, depending on individual variation in metablism. Some references say the half life is between 9 and 20 hours. It is very difficult to know how quickly a given individual will metabolize a specific drug. Bromazepam's duration is shorter than that of diazepam (Valium), which has a long acting, active metabolite.
Although bromazepam is not approved by the FDA for use as of November 2002, it is Schedule IV (along with most of the other benzodiazepines). It acts on the same site on GABA receptors that diazepam does and can be antagonized by the benzodiazepine antagonist Flumazenil.
Some useful links:
http://www.inchem.org/documents/pims/pharm/pim281.htm
http://home.intekom.com/pharm/lennon/brazepam.html
http://www.behavenet.com/capsules/treatments/drugs/bromazepam.htm
http://www.edoc.co.za/medilink/actives/137.html
See also, our Benzodiazepine Vault
This isn't a lot of info, but hopefully it will help some.
aloha
psilo |
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Categories:
[ Pharmacology ]
[ Benzodiazepines ]
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