Ask Erowid

Ask a Question


Find an answer:

View By Category

Search Ask Erowid
Search Vaults


Enter a keyword in the search field above to look up a question or answer on a specific topic.

Off-Site Psychoactive Question Resources
  Ask Dr Shulgin

Resources at Erowid
  Plants & Drugs
  Freedom & Law
  Mind & Spirit
  Arts & Sciences
  Library / Bookstore
  What's New
  About Erowid
  .
Q: I write for to ask yours about some informations on the pharmacology and pharmacokynetics of Bromazepam (benzodiazepinic drug). I seek by this information on the Erowid pages but I can't find nothing I want.

A: Bromazepam is a short to medium acting benzodiazepine similar to alprazolam (Xanax) most often used in the treatment of anxiety. It is a Central Nervous System (CNS) depressant. It is considered to have a half-life of between 8 and 30 hours, depending on individual variation in metablism. Some references say the half life is between 9 and 20 hours. It is very difficult to know how quickly a given individual will metabolize a specific drug. Bromazepam's duration is shorter than that of diazepam (Valium), which has a long acting, active metabolite.



Although bromazepam is not approved by the FDA for use as of November 2002, it is Schedule IV (along with most of the other benzodiazepines). It acts on the same site on GABA receptors that diazepam does and can be antagonized by the benzodiazepine antagonist Flumazenil.



Some useful links:

http://www.inchem.org/documents/pims/pharm/pim281.htm

http://home.intekom.com/pharm/lennon/brazepam.html

http://www.behavenet.com/capsules/treatments/drugs/bromazepam.htm

http://www.edoc.co.za/medilink/actives/137.html



See also, our Benzodiazepine Vault






This isn't a lot of info, but hopefully it will help some.



aloha

psilo

Asked By : Mário Henrique R. Bernardes, researcher
Answered By : psilo
Published Date : 10 / 15 / 2002
Last Edited Date : 11 / 26 / 2002
Question ID : 2992

Categories: [ Pharmacology ] [ Benzodiazepines ]



Ask Erowid v1.7 - Jul, 2005

(content and html © the Vaults of Erowid. Please ask permission before publicly reproducing.)