There has been a long standing myth in my area regarding eating chocolate on MDMA. I've read that use of an MAOI with chocolate can be risky, but MDMA isn't actually a MAOI, right?
||The primary interaction to be aware of is mixing MAOIs with MDMA. This should be avoided.|
MDMA is not an MAOI. There is, however, a persistent rumor that chocolate itself is an MAOI. The primary support given for this seems to be something that Terence McKenna once said about the Mayan custom of mixing chocolate with mushrooms (suggesting they did this to potentiate the mushrooms with the chocolate). Regardless, we have not been able to find any solid evidence that chocolate is, in fact, an MAOI.
The point of confusion is certainly that chocolate contains caffeine and theobromine, whose effects may be increased when taken in combination with an MAOI. Many sources suggest that chocolate should not be eaten incombination with prescription MAOIs, although the levels of caffeine and theobromine are low enough that reliable sources generally say it is safe in combination with MAOIs unless the chocolate is eaten in large quantities.
Many people get confused between MAOIs, and the foods and medications which should not be mixed with them. As neither MDMA nor chocolate are MAOIs, combining them should not be a problem. We have never received a report of health problems resulting from mixing chocolate with MDMA.
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