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What are the effects of nitroglycerin and amitryptaline?
Q: I have a Nitroglycerin transdermal patch and some amitryptaline. What does nitroglycerin do? How is amitryptaline used? (bump, swallow and drink on it?) i know it's an anti-depressent w/some sort of stimulents in it. i just wasn't sure what to do with it.

A: Nitroglycerin is a powerful vasodialator (opens your blood vessels). It is usually used to treat angina (reduced blood flow supplying the heart). While it may have effects similar to amyl/butyl/other nitrates ("Locker Room", "Rush", etc) I would reccomend NOT taking this recreationally, as the Merck Index lists some pretty nasty side effects and toxic effects such as headaches, hypotension, heart palpitations, tachycardia (fast heartrate), abdominal pain, nausea, and retching.

Amitryptaline is a tricyclic antidepressant (one of the older classes of antidepressants). It does not have stimulant effects. However, the tricyclics were known to have varying side effects, sometimes different between different people (thus the desire for "second generation" anti-depressants such as prozac and other SSRIs). There is little if any recreational value in taking a tricyclic antidepressant, and it can be quite dangerous to mix it with other drugs (such as alcohol, other antidepressants, MAOIs, MDMA, etc (note I said *dangerous*, not "fun").

Again, I do not recommend taking either of these drugs recreationally.



Asked By : Adam
Answered By : psilo
Published Date : 2 / 20 / 2001
Last Edited Date : 2 / 20 / 2001
Question ID : 2290

Categories: [ Pharmaceuticals ]

Ask Erowid v1.7 - Jul, 2005

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