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Slikker W Jr, Gaylor DW. 
“Biologically based dose-response model for neurotoxicity risk assessment”. 
Ann N Y Acad Sci. 1995;765:339.
The regulation of neurotoxicants has usually been based upon setting reference doses by dividing a no observed adverse effect level by uncertainty factors that theoretically account for interspecies and intraspecies extrapolation of experimental results in animals to humans. Recently, we proposed a four-step alternative procedure, which provides quantitative estimates of risk as a function of dose.
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