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Addy PH, Garcia-Romeu A, Metzger M, Wade J. 
“The subjective experience of acute, experimentally-induced Salvia divinorum inebriation”. 
J Psychopharmacol. 2015 Feb 18.
This study examined the overall psychological effects of inebriation facilitated by the naturally-occurring plant hallucinogen Salvia divinorum using a double-blind, randomized, placebo-controlled trial. Thirty healthy individuals self-administered Salvia divinorum via combustion and inhalation in a quiet, comfortable research setting. Experimental sessions, post-session interviews, and 8-week follow-up meetings were audio recorded and transcribed to provide the primary qualitative material analyzed here. Additionally, post-session responses to the Hallucinogen Rating Scale provided a quantitative groundwork for mixed-methods discussion. Qualitative data underwent thematic content analysis, being coded independently by three researchers before being collaboratively integrated to provide the final results. Three main themes and 10 subthemes of acute intoxication emerged, encompassing the qualities of the experience, perceptual alterations, and cognitive-affective shifts. The experience was described as having rapid onset and being intense and unique. Participants reported marked changes in auditory, visual, and interoceptive sensory input; losing normal awareness of themselves and their surroundings; and an assortment of delusional phenomena. Additionally, the abuse potential of Salvia divinorum was examined post hoc. These findings are discussed in light of previous research, and provide an initial framework for greater understanding of the subjective effects of Salvia divinorum, an emerging drug of abuse.
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Mar 11, 2015 23:27
Newsweek Article about Research #

Getting High on Salvia, for Science BY DOUGLAS MAIN 3/1/15 AT 10:45 AM

Some people literally forgot which way was up, or didn’t know if they owned their bodies anymore. Others felt their internal organs being pulled in directions across all three planes, and through extra dimensions they hadn’t known existed. And a few could “feel” objects by looking at them.

All these reports come from people smoking an herb in the sage family calledSalvia divinorum, commonly referred to as salvia. This plant has been used in religious ceremonies by the Mazatec people of Mexico for centuries. They associate it with the Virgin Mary, and believe ingesting salvia enables them to speak with her.


Peter Addy, a researcher who is now at Yale University, decided to conduct the first large study to describe the subjective effects of smoking salvia. While still at the Institute of Transpersonal Psychology in Palo Alto, California, Addy got 30 participants to smoke salvia in a relaxed setting, in a lab, while seated next to him. (A medic was standing by outside, but was never needed.) Addy sat next to each person while they smoked a pre-prepared sample of the herb, and after the 10- to 15-minute trip, talked with them about their experiences.
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