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Schultes RE. 
“Indole alkaloids in plant hallucinogens”. 
Planta Med. 1976 Jun 01;29(4):330-42.
Many psychoactive plants owe their activity to structures containing an indole nucleus. This nucleus is evident in the synthetic LSD and in such well known compounds as yohimbine, reserpine, physostigmine and the strychnos alkaloids. And it is to the presence of indole alkaloids that many of the most striking hallucinogenic plants owe their biodynamic activity: iboga in Africa (with ibogaine and related alkaloids); the sacred mushrooms (with psilocybine) and morning glories (with ergoline alkaloids) of Mexico; and, in South America, the drinks called ayahuasca (with 0-carbolines) and in vinho de jurema (with N,N-dimethyltryptamine) and the snuffs known as yopo, huilca and epena (all with various tryptamines).
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