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McCann UD, Szabo Z, Scheffel U, Dannals RF, Ricaurte GA. 
“Toxic effect of MDMA on brain serotonin neurons”. 
Lancet. 1999 Apr 10;353:1270.
Sir -- Lawrence Reed and co-workers underscore the inherent difficulties of retrospective studies in individuals who have used illicit substances, and question whether amphetamine, LSD, cocaine, and cannabis might also lead to reductions in the serotonin transporter. Neither cocaine nor amphetamine is toxic toward brain serotonin neurons and the structural requirements for substituted amphetamine neurotoxicity are quite strict...
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