Ayahuasca: alkaloids, plants & analogs
Section 2 :
Ayahuasca Analog MAOI source plants
Reported effective species (a very short list)
Passiflora incarnata The isolate from several hundred grams of dried foliage and stems was reported effective, but rough, by Gracie & Zarkov. It should be added that the simple harman alkaloids are the main components in Passiflora. These should not be consumed in any great quantity.
Based on rat studies, they are believed to be potentially harmful to the kidneys and carcinogenic if ingestedin large quantities. They are endogenous compounds and pose no risk if taken in smaller amounts.
While no specific data exists, for Gracie & Zarkov to have ingested an effective dose of Harmine from P. incarnata, it would have been accompanied by a much larger dose of Harman. (Harman was found ineffective as an oral activator for DMT but was only evaluated up to 250 mg orally.) Other Passiflora species MIGHT prove useful; but this area is underexplored.
For instance Passiflora rubra hints at being potentially useful as it has the common names "pomme-liane zombie" and "Dutchman's laudanum" (English) but we can locate nothing concerning an analysis or its reported pharmacology or folk applications.
Peganum harmala Highly variable.
3 to 5 grams of dried seeds is common. (a level to a heaping teaspoon) Some are stronger or weaker. Roots are also potent and useful. Other plant parts should be avoided.