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Toxic Cocktail
Divalproex, Fluvoxomine, Remeron, Risperidone, Zopiclone & Cannabis
by Darkstar
Citation:   Darkstar. "Toxic Cocktail: An Experience with Divalproex, Fluvoxomine, Remeron, Risperidone, Zopiclone & Cannabis (exp60867)". Feb 5, 2008.

2000 mg oral Pharms - Divalproex (daily)
  250 mg oral Pharms - Fluvoxamine (daily)
  2.0 mg oral Pharms - Risperidone (daily)
  45 mg oral Pharms - Mirtazapine (daily)
    smoked Cannabis  
  11.25 mg oral Pharms - Zopiclone  
  7.5 mg oral Pharms - Zopiclone  


It was getting late in the evening in downtown apartment on a Monday night, when the phone rang. It was my fiends Jeremy who is the lead singer of a band. As usual, Jer was in search of some weed, and I was usually the guy who sold it to him. But, I had quit smoking weed for three months at this point, because I wanted to improve my OCD and bipolar disorder. Nevertheless, I ended up finding it for him anyway, and I could resist the temptation of smoking a cone. It was especially tempting because I wanted to see how my latest prescription, Imovane, would react when combined with cannabis use.

It was now a only little while after taking my nightly regimen, that was to include a combination of the following: 2000mg Divalproex, 250mg Fluvoxomine, 2mg Risperidone, 45mg Mirtazapine, and the more recent addition, 7-15mg Zopiclone. Tonight I had only taken one and a half of the 7.5 mg Imovane tablets.

After A while of sitting on the couch in my medicated daze, I began to obsess over the small amount of reefer that I had pinched out of the bag for myself. With in a matter of minutes I had rolled one up and was smoking it. Soon I was completely fucking blazed. Everything was fucking amazing for a while, and I felt like I had taken a small amount of mushrooms, smoked weed, and drank a bit of hard alcohol.

Eventually I ended up in my bed, talking on the phone with my ex-girlfriend for about an hour. She told me that I sounded all “doped up”, and she also asked me if I was okay. But I felt absolutely fine..

The suddenly, a wave of unbearable nausea came over my whole body, an my mind when into some kind of trance, sort of like the k-hole. I then felt like I had to take a shit and ran for the bathroom. I sat on the toilet and pissed out of my asshole for a while. Afterwards, I went back to lay in me bed but this time brough a garbage can to throw up in, and I did. I puked up the most acidic mixure ever concocted. This fucking shit burned my throat and mouth. This phase lasted about an hour and a half.

When the whole thing passed I still felt like a can of smashed ass-holes, and I couldn’t get to sleep. I decided to take another Zopiclone, and It was good night for me. I will never smoke weed again as long as I am on these medications. The consequences of doing so were not worth it. I blame it on the Depakote mainly, but who knows? I don’t want to go through that shit again.

Exp Year: 2006ExpID: 60867
Gender: Male 
Age at time of experience: Not Given 
Published: Feb 5, 2008Views: 34,261
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Pharms - Mirtazapine (311), Pharms - Risperidone (253), Pharms - Zopiclone (272), Cannabis (1), Pharms - Divalproex (275), Pharms - Fluvoxamine (297) : Health Problems (27), Medical Use (47), Combinations (3), Small Group (2-9) (17)

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