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Successfully Eliminating Urinary Retention
Methallylescaline, Tamsulosin, Phenibut, Losartan & Propranolol
Citation:   At0micFury. "Successfully Eliminating Urinary Retention: An Experience with Methallylescaline, Tamsulosin, Phenibut, Losartan & Propranolol (exp117758)". Erowid.org. Jun 13, 2025. erowid.org/exp/117758

 
DOSE:
T+ 0:00
400 mg oral Smarts - Phenibut  
  T+ 1:00 400 mg oral Smarts - Phenibut  
  T+ 1:00 0.1 mg oral Pharmaceuticals  
  T+ 3:00 400 mg oral Smarts - Phenibut  
  T+ 3:00 50 mg oral Pharms - Losartan  
  T+ 3:00 10 mg oral Pharms - Propranolol  
  T+ 3:00   oral Ginger (extract)
  T+ 4:00 80 mg oral Methallylescaline  
  T+ 9:00 0.1 mg oral Pharmaceuticals  
  T+ 36:00 200 mg oral Smarts - Phenibut  
BODY WEIGHT: 135 lb
TLDR: 0.2mg of Tamsulosin is effective for significantly reducing Methallylescaline induced urinary retention. 80mg [MAL] increased undesirable physical side effects much more than psychedelic effects compared to 70mg. Nausea and stomach cramps were the worst side effects experienced and ginger extract capsules were woefully insufficient to manage it. Next time, for 80mg and higher, I will definitely use a prescription strength anti-nausea medication such as Ondansetron.

Set and Setting: Alone in my room at night. I was mildly depressed but otherwise had a fine mental set.

T-4hr: 400mg Phenibut

T-3hr: 400mg Phenibut, 0.1mg Tamsulosin

T-1hr: 400mg Phenibut, 50mg Losartan, 10mg Propranolol, ginger extract

T+0hr: MAL 80mg



Phenibut was staggered to (possibly) enhance absorption and to reduce nausea. It’s used to alleviate come up anxiety, although the chill nature of MAL means that less or even no Phenibut could have been used. However, I like using 1.2g when trying a higher dosage of any psychedelic. Losartan is for vasoconstriction, Propranolol is for preventing physical anxiety and high heartrate, Tamsulosin is for urinary retention.

T+1hr: First visuals appear. I feel pretty nauseas, so I take more ginger.

T+1.5hr: A sudden wave of nausea overcomes me and causes me to puke. I was hoping that I would puke at least a little later into the experience. It is clear that the ginger extract is insufficient for this dose of MAL, although I avoided puking on a previous 70mg experience.
It is clear that the ginger extract is insufficient for this dose of MAL, although I avoided puking on a previous 70mg experience.


T+3hr: I reach the peak of the experience. Despite puking relatively early, the experience continued to come up normally and was stronger than the 70mg experience with no puking, suggesting that it got mostly absorbed.

The OEV geometry was stronger and more apparent than 60/70mg of MAL but was not phenomenologically different in character. An exception to this is when I hallucinated lighting flashes (but not bolts) off in some distant clouds, but otherwise there were no external objects, people, or entities hallucinated in contrast to other experience reports for both MAL and Mescaline, to my disappointment. Colors were much more vibrant, but hallucinated colors were not much more present than 60mg.

The CEVs were quite interesting. Perceived visual geometry was visible although it was not much stronger than 70mg and definitely not as strong as lysergimides or tryptamines. What was much stronger was visual imagination. What I mean by this is that in normal waking life, visual imagination exists in a sort of separate space or world (at least for people without aphantasia) and I am able to switch my attention from actual sensory perception to this internal space. This is no different on MAL where perceived visual geometry and internal imagination exist separately with eyes closed. The difference is that this internal imagination did its own thing and showed me scenes, people, and objects without direct control by me. This internal imagination was trippy in character, but visual geometry was not present. It was extremely vivid and almost comparable to actual perception. I wouldn’t be surprised if it did become actual perception in higher dosages.

Slight ego death was present but not much stronger than with 70mg. The ego death was anything but anxiety inducing and was more comforting to experience. It wasn’t really forced on me either, it was only present when I closed my eyes and let it happen.

Stimulation was comparable to a moderate dose of amphetamine and a bit stronger than 2-FMA. It became most notable after the peak.

The physical side effects increased far more than the psychedelic effects in the jump from 70 to 80mg. As mentioned earlier, I puked early on in the experience, but I also puked 3 other times at various points in the experience. The nausea would come on suddenly and leave for a while after purging, although it inevitably came back. I also experienced strong abdominal cramps throughout the experience that were more persistent than the nausea. Thankfully laying on my back alleviated both the nausea and cramps, although the second I sat upright they would rush back. I ended up spending nearly the entire comedown laying down because it was so bad.

The main concern I had going into this trip based on my previous experience was urinary retention. Because of this, I bought Tamsulosin which is a medication that is used to treat urinary retention. I took 0.1mg 3 hours before the MAL. Later on in the experience I noticed that I still had urinary retention, although this didn’t surprise me as 0.1mg is less than the typically prescribed dose for treating normal UR. I took another 0.1mg about 5 hours into the experience and within an hour or two I had essentially no issue urinating. This is in contrast with 60 and 70mg where I wasn’t able to produce a decent stream of urine until around 11 hours into the experience and was only possible when putting a warm water bottle on my lower abdomen. I did not need to use a warm water bottle at all for this experience. This suggests that Tamsulosin is effective for essentially eliminating the UR induced by MAL.

An interesting effect was that muscles deep inside my legs and other parts of my body were spasming throughout the first half of the trip
muscles deep inside my legs and other parts of my body were spasming throughout the first half of the trip
. These spasms weren’t uncomfortable but were not something I have experienced with any other psychedelics. Additionally, I experienced other motor symptoms typical of psychedelics such as hand shaking, jaw shivering, slight nystagmus (nothing compared to MDMA or 5-MAPB), as well as the irresistible urge to move my appendages around aimlessly and run my fingers through my hair.

The body high, or rather the lack thereof, was the most disappointing aspect of this trip. 40mg and 60mg trips have produced more consistent body euphoria than this dose despite being significantly lower dosages. I have a couple theories as to why: I had been using THC recently (although I abstained for a few days beforehand). I have previously encountered the same loss of body high with 2C-B, and I noticed that the weakest body highs always occurred when THC had been used recently. Additionally, it’s possible that there might be a long-term tolerance to the “magic” similar to MDMA, although I am unconvinced of this due to the different pharmacology and the fact that it had been well over a month since I had previously tripped. Finally, it’s entirely plausible that there is no physiological tolerance but instead a psychological tolerance and lack of novelty that caused this to occur. I think this might be the most likely reason given that my most euphoric experiences with both 2C-B and MAL have been within my first few experiences. There were virtually no empathogenic effects in contrast to my other experiences.

T+6hr: Visuals start to die down although cognitive effects still continue for a while longer. I was trapped in my bed due to fear of puking again. I occasionally get up to use the bathroom and urinate without issue. The stimulation increased and so did my motor symptoms for the next couple hours before dying down.

T+14hr: The nausea and abdominal cramps reduced enough that I could get up and eat some food. I had strong cramps for a little while after eating but no nausea. Visual and cognitive effects are slightly present but mostly gone. Motor symptoms died down significantly but were still quite present. I felt quite exhausted both physically and mentally at this point. Sleep deprivation was mostly responsible for cognitive fatigue, and the physical exhaustion was likely a result of my constant squirming.

T+21Hr: No visuals besides some visual snow but there are still some slight motor effects. There is a nice afterglow. I sleep around this time.

T+36Hr: 200mg Phenibut. I find that doing a rapid taper after a larger dose of Phenibut is effective for completely eliminating rebound anxiety and depression. For 1.2g I take 200mg around 36 hours after the initial dose and cut that dose in half each successive day until I reach 25mg.

I slept for 14 hours and still felt kind of tired. This is the last time I’m doing a longer lasting psychedelic at night. At least tryptamines allow me to sleep after they wear off. I had some Trazodone I could have used to sleep earlier, although I wanted to experience the full duration of effects. There was a nice antidepressant effect the next day but not much stronger than 60mg.

Overall, this trip was kind of disappointing. I was hoping for much stronger psychedelic effects but instead got much stronger physical side effects. I own Ondansetron, but I did not physically have it with me for this trip. Next time I will definitely use it. I am glad that Tamsulosin worked well for alleviating urinary retention with no noticeable side effects, I will be using it with MAL from now on.

Exp Year: 2023ExpID: 117758
Gender: Male 
Age at time of experience: 20
Published: Jun 13, 2025Views: Not Supported
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Smarts - Phenibut (379), Methallylescaline (586) : Alone (16), Health Problems (27), Combinations (3)

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