Anti-Depressant Microdosing
Syrian Rue & 5-HTP
Citation:   PinkFluffyUnicorns. "Anti-Depressant Microdosing: An Experience with Syrian Rue & 5-HTP (exp108918)". Jul 28, 2016.

  oral St. John's Wort (daily)
  100 mg oral Tryptophan - 5-HTP (daily)
  100 mg oral SAMe (daily)
  1 shot oral Syrian Rue (extract)
Today I started taking approx .25g daily of Syrian Rue as an alternative to pharmacological anti-depressants and as an adjunct to herbal ones. After major psychological trauma I was prescribed one after the other of SSRI's - all of which gave me horrific side effects.

I currently take St. Johns Wort (tincture) / 5HTP (100mg) / SAMe (100mg) but still needed something extra.
As Syrian Rue is an MAOI I am presuming it will potentiate the effects of the St. John's / 5HTP / SAMe.

I boiled 5grams of rue in 300mls of water for one hour then crushed the seeds as much as possible and strained and cooled. I ended up with 130 mls of rich yellow tincture that I took as 10ml shot.

After approx one hour I noticed a mild painkiller effect and I found I was fully engaged in what I was doing (whereas normally I feel a constant detachment from people and activities). After 4 hours I still feel more motivated than I have in months.

I plan to take my 20 doses that I boiled up tonight, 1 x day for the next 20 days then stop for a couple of weeks and see what happens. I really wish I could hear from others that might have done something similar.

Exp Year: 2016ExpID: 108918
Gender: Female 
Age at time of experience: 37
Published: Jul 28, 2016Views: 3,877
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Syrian Rue (45), Tryptophan (138) : Alone (16), Therapeutic Intent or Outcome (49), Depression (15), General (1)

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