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Hellishly Anxious and Slow Come-Up
LSZ & Cannabis
by Lysergamided
Citation:   Lysergamided. "Hellishly Anxious and Slow Come-Up: An Experience with LSZ & Cannabis (exp103838)". Nov 5, 2015.

T+ 0:00
1 hit oral LSZ (blotter / tab)
  T+ 0:47 .5 joints/cigs smoked Cannabis  


This was my second experiment with LSZ , my first being a week before this one. LSZ is an interesting compound with one isomer of it being more potent then LSD. It has other isomers that are active unlike LSD.

9:00am I drop 1 blotter on my tongue and wait. I observe the blotter tastes like ink slightly but mainly like paper.

9:05am I have held it on my tongue for 5 minutes now, with no numbness present which would indicate the substance on the blotter is not a NBOME.

9:15am I decide to swallow the blotter.

9:30am It hasnít hit me yet but last time I took LSZ it didnít take action till about an hour after taking it.

9:45am I decide to roll a joint feeling something from the LSZ but itís very subtle.

9:47am Woah, after having a few puffs my HPPD suddenly increased, odd because it doesnít increase from just cannabis alone anymore.

9:50am I put the joint out so I can save the rest for later feeling like I am coming up now. euphoria is noted and is steadily increasing. Small changes in visual field has started and sound distortion is occurring.

10:04am I looked at my pupils in the mirror no dilation as of yet.

10:19am Definitely starting to feel the serotonin activity but still no pupil dilation.

10:24am I decide to put on music while coming up the visual phenomena is starting to increase slowly.

10:31am I notice my hands are shaking from anxiety. This exactly like the last time I did LSZ as I got a lot of similar effects to compounds that mainly increase dopamine.

10:45am Mucus and saliva production has increased. I look at my floor, the carpet is moving around in patterns. Headache is noted.

11:00am I start peaking the anxiety is very strong, I might end up taking ativan 1mg to calm myself down.

11:55am after laying down and getting thru the hellish come-up I start feeling ďOKĒ again. Stomach discomfort is noted and is getting annoying.

12:47pm I looked at my pupils and they were slightly dilated not as dilated as LSD dilates them. It was similar to how much methylphenidate dilates my pupils which isnít a lot but noticeable. Visuals are apparent and are similar to a 100 mic dose of LSD. They were weaker then my last experiment.

Unknown time: I spent the next few hours laying on my bed thinking, relaxing and enjoying the psychedelia.

3:15pm I feel like I am starting to come down.

5:31pm I am sober now.

I would rate this experience as being a ++ on Shulginís rating scale. My last experiment was a +++ at 300 micrograms.

This was a good experience worth repeating but the come-up of LSZ has been hellishly anxious for me and slow. The stomach discomfort was more apparent this experiment. I have given friends this substance and they reported no anxiety at all during their experiences so that is an individual reaction. I find LSZ is something to repeat and is enjoyable but I donít think it will carry on much like how LSD did.

[Reported Dose: 150 micrograms]

Exp Year: 2013ExpID: 103838
Gender: Male 
Age at time of experience: 18 
Published: Nov 5, 2015Views: 5,787
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LSZ (609) : General (1), Unknown Context (20)

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