|1910||MDA first synthesized by G. Mannish and W. Jacobson 1|
|1939||Animal tests are first performed with MDA. 1|
|1941||First human trials with MDA as part of an exploration of possible therapies for Parkinsonism. 2|
|1949-1957||MDA studied as a potential antidepressant and/or anorexic agent by Smith, Klein & French. More than 500 people were given MDA during the course of this investigation. [More Info]|
|Jan 8, 1953||Harold Blauer dies of an overdose of MDA (code name EA-1298) during an army-sponsored drug experiment. The army was working to develop new "truth serums" or incapacitating agents and injected Blauer with 500 mg MDA IV. 3 [Details] [More Info]|
|1957||Gordon Alles describes the MDA experience at a conference in Princeton New Jersey, sponsored by the Josiah Macy, Jr., Foundation. The proceedings of the conference were published two years later (1959) in Neuropharmacology: Transactions of the 4th Conference. 1|
|1958-1961||MDA is patented by several different groups...as a cough suppressant by H.D. Brown (1958), as an ataractic by Smith, Kline, and French, Co. (1960), and as an appetite suppressant under the trade name "Amphedoxamine" (1961). 2|
|May 17, 1961||Dr. Alexander Shulgin first tries MDA at a dose of 4.8 mg. After this single dose Dr. Shulgin would not try MDA again until four years later in 1965. 4 [Details] [More Info]|
|1963-1964||MDA begins showing up in the counterculture. 1|
|Oct 1967||The U.S. Bureau of Drug Abuse Control reports in its publication Micro-gram their "first encounter with the compound [MDA]". 5 [Details] [More Info]|
|Oct 27, 1970||The Comprehensive Drug Abuse Prevention and Control Act is passed. Part II of this is the Controlled Substance Act (CSA) which defines a scheduling system for drugs. It places most of the known hallucinogens (LSD, psilocybin, psilocin, mescaline, peyote, cannabis, & MDA) in Schedule I. It places coca, cocaine and injectable methamphetamine in Schedule II. Other amphetamines and stimulants, including non-injectable methamphetamine are placed in Schedule III.|
|1980-2000||MDA continues to be used recreational, often sold in tablet form as 'ecstasy'.|
- Stafford P. Psychedelics Encyclopedia. Ronin. 1992.
- Pentney AR. "An Exploration of the History and Controversies Surrounding MDMA and MDA". J Psychoactive Drugs. Jul-Sep 2001;Vol 33(3).
- Lee MA, Shlain B. Acid Dreams: The CIA, LSD and the Sixties Rebellion. Grove, 1985.
- Shulgin AT. Pharmacology Notes I. Page 37.
- Microgram Editors. "Methylenedioxy Amphetamine". Microgram. Bureau of Drug Abuse Control. Feb 1968. 1(5):4-5.