Erowid References Database
Ott J.
“Pharmahuasca, Anahuasca and Vinho da Jurema: Human Pharmacology of Oral DMT Plus Harmine”.
Yearbook for Ethnomedicine. 1997.
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Abstract
A summary is presented of human self-experiments or psychonautic bioassays of pharmahuasca capsules containing crystalline N,N-dimethyltryptamine (DMT) plus harmine, as well as combinations of other psychoactive tryptamines with other beta-carbolines. The 1967 HOLMSTEDT-LINDGREN hypothesis of the ayahuasca effect-oral psychoactivity of DMT consequent to monoamine-oxidase [MAO] inhibition from concomitant ingestion of beta-carbolines- has been confirmed by 8 self-experimenters. Results of a total of some 70 bioassays are summarized and the literature on this subject is reviewed. Discussion of ayahuasca analogues (anahuasca) focuses on the contemporary non-traditional use of jurema preta (Mimosa tenuiflora) and the ethnobotany and human pharmacology of traditional vinho da jurema is also reviewed [with 94 references and 1 Table].
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