Sir-The finding of U D McCann and colleagues of reduced serotonin transporter binding in heavy users of MDMA lends support to evidence of the harmful effect of this drug on the serotonin system, which was previously reported in animals.2 However, as the investigators acknowledge, little is known of the functional effects of MDMA-induced brain serotonin neurotoxic lesions. We report the effect of long-term consumption of MDMA on cognitive function.
