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“Discovery of psychoactive plant and mushroom alkaloids in behavior-modifying fungal cicada pathogens”. 
bioRxiv. 2018 July 30.
Entomopathogenic fungi routinely kill their hosts before releasing infectious conidia, but select species keep their hosts alive while sporulating to enhance spore dispersal. Recent expression and metabolomics studies involving host-killing entomopathogens have helped unravel infection processes and host responses, yet the mechanisms underlying active host transmission in insects with Entomophthoralean fungal infections are completely unexplored. Here we report the discovery, through global and targeted metabolomics supported by metagenomics and proteomics, of the plant amphetamine, cathinone, in Massospora cicadina-infected periodical cicadas, and the mushroom tryptamine, psilocybin, in M. platypediae- and M. levispora-infected annual cicadas. The neurogenic activities of these alkaloids provide a hypothetical framework for a chemically induced extended phenotype of Massospora that alters cicada behavior by increasing endurance and suppressing feeding prior to death.
Comments and Responses to this Article
Oct 19, 2018 14:42
See also another paper about insects infected with psychoactive fungi #

See also: Doan UV, Mendez Rojas B, Kirby R. "Unintentional ingestion of Cordyceps fungus-infected cicada nymphs causing ibotenic acid poisoning in Southern Vietnam" Clin Toxicol (Phila). 2017 Sep 07;55(8):893-896.
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