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Bordo DJ, Dorfman MA. 
“Ecstasy overdose: rapid cooling leads to successful outcome”. 
Am J Emerg Med. 2004 Jul 19;22(4):326-7.
To the Editor: — Ecstasy, 3,4 Methlyenedioxymethamphet- amine, was fi rst developed in Germany in the early 1900s as an appetite suppressant. Later in the century, psychotherapists used it with patients to enhance communication during therapy. The drug, with its mood altering properties, combined with the stimu- lant effects of an amphetamine, found its greatest use in Great Britain at so called “rave parties in the 1970s and 1980s and has become quite prevalent on American college campuses.

We report the case of a 20-year-old woman who had ingested ecstasy and subsequently presented to the emergency department (ED) in an unresponsive state. She was diaphoretic, tachycardic, and had a rectal temperature of 107.2 F. The patient underwent cool water misting and evaporation in addition to ice water lavage. The patient was successfully treated and was discharged home 9 days after admission without any significant sequelae.

The ED was notified via telemetry of a 20-year-old woman who had ingested ecstasy earlier in the evening. Her boyfriend called 911 when the woman became unresponsive. Paramedics found the woman to be mildly responsive to painful stimuli, with a heart rate in the 170s with a palpable blood pressure. There was no evidence to suggest any other coingestion.
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