Erowid
 
 
Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Erowid References Database
Gilsdorf RT, Nord FF. 
“STUDIES ON THE CHEMISTRY OF HETEROCYCLICS. IX. REDUCTION OF THIENYL NITROOLEFINS WITH LITHIUM ALUMINUM HYDRIDE'”. 
The Department of Organic Chemistry and Enzymology. 1950 Jan 16;? (193):807-11.
Abstract
A new and direct synthesis of the pharmacologically active P-(2-thienyl)ethylamine (1, 2) and 8-(2-thienyl)isopropylamine (2, 3), the thiophene analogue of Benzedrine, has been developed. The successful condensation of the readily available 2-thenaldehyde and various substituted 2-thenaldehydes (4) with nitromethane and 2-thenaldehyde with nitroethane to form the corresponding nitroolefins, was recently reported (5). These latter compounds have now been satisfactorily reduced to the desired saturated amines.
Comments and Responses to this Article
#
Submit Comment
[ Cite HTML ]