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Bogart GT, Ott CA. 
“Abuse of second-generation antipsychotics: What prescribers need to know”. 
Current Psychiatry. 2011 May;10(5):77-79.
[No Abstract]

Practice Points

• Antipsychotics have been abused and misused by inpatients and outpatients.

• Most published case reports of antipsychotic abuse involve quetiapine, although some describe misuse of other agents, including olanzapine.

• Serotonin, histamine, and α-adrenergic neurotransmitter systems may play a role in second-generation antipsychotics’ abuse potential.

• Although individuals have misused quetiapine and olanzapine, evidence indicates that these drugs may be effective for treating substance use disorders.
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