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Jones HE, Herning RI, Cadet JL, Griffiths RR. 
“Caffeine withdrawal increases cerebral blood flow velocity and alters quantitative electroencephalography EEG activity”. 
Psychopharmacology Berl. 2000 Jan 28;147(4):371-7.
Abstract
Cessation of daily caffeine consumption produces a withdrawal syndrome comprised of subjective symptoms and functional impairment. Few controlled studies have examined the physiological effects of caffeine withdrawal.
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