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Appel JB, Freedman DX. 
“Tolerance and Cross-Tolerance Among Psychotomimetic Drugs”. 
Psychopharmacologia. 1968 Sep 21;13(3):267-74.
A fixed-ratio schedule of milk reinforcement (FR 30) was used to study tolerance to the effects of D-LED, L-LSD, BOL, psilocybin, mescaline, and n-amphetamine in the rat. A decrease in the amount of disruption of bar-pressing occurs with repeated daily administration of appropriate doses of all of the "psychotomimetic" compounds, and cross-tolerance was also demonstrated.
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