Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Erowid References Database
Sheffler DJ, Roth BL. 
“Salvinorin A: the 'magic mint' hallucinogen finds a molecular target in the kappa opioid receptor”. 
Trends Pharmacol Sci. 2003 Mar 11;24(3):107-9.
Salvinorin A, a neoclerodane diterpene, is the most potent naturally occurring hallucinogen known and rivals the synthetic hallucinogen lysergic acid diethylamide in potency. Recently, the molecular target of salvinorin A was identified as the kappa opioid receptor (KOR). Salvinorin A represents the only known non-nitrogenous KOR selective agonist. Based on the selectivity of salvinorin A for the KOR, this receptor represents a potential molecular target for the development of drugs to treat disorders characterized by alterations in perception, including schizophrenia, Alzheimer's disease and bipolar disorder.
Comments and Responses to this Article
Submit Comment
[ Cite HTML ]