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Winter JC. 
“The Stimulus Effects of Serotonergic Hallucinogens in Animals”. 
NIDA Research Monograph. 1994 Oct;146:157-82.
Mankind has known of naturally occurring hallucinogens for thousands of years (Schultes and Hofmann 1980), but less than one-tenth of one millennium has passed since it could be said with confidence that a pure chemical of known structure is hallucinogenic (Heffter 1897; Spath 1919). That chemical was mescaline, a representative of the phenethylamine subclass of the serotonergic hallucinogens. The other subclass, the indoleamines, is perhaps best represented by lysergic acid diethylamide (LSD), a drug whose hallucinogenic properties were discovered by Albert Hofmann on April 16, 1943 (Hofmann 1959). That both the indoleamines and the phenethylamines are properly classified together as serotonergic hallucinogens has become apparent only in the last 2 decades.
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