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Grof S, Soskin RA, Richards WA, Kurland AA.
“DPT as an adjunct in psychotherapy of alcoholics”.
Int Pharmacopsychiatry. 1973 Jun;8(1):104-15.
The usefulness of dipropyltryptamine (DPT) as an adjunct to psychedelic therapy was explored in a pilot study caIried out on 51 alcoholic patients from the Alcoholic Rehabilitation Unit at Spring Grove State Hospital. The evaluation of the results was based on the compaIison of pre- and posttreatment results of a battery of psychological tests and of pretreatment and follow-up ratings of an independent team of social workers. The psychological tests involved the Minnesota multiphasic personality inventory (MMPI), Personal orientation inventory (POI), Raven progressive matrices, Psychiatric evaluation profile (PEP), and Benton visual retention test. The social history questionnaire used by the social workers for assessment of the patients' adjustment consisted of 0-10-point scales measuring residential, occupational and interpersonal adjustment, abstinence, and global adjustment.
A dramatic improvement was observed on a variety of psychological test variables; in many of them the pre- and postdifferences reached a high level of statistical significance. From a total of 51 patients included in the study, 47 (92.1 %) could be located for followup assessment. In this follow-up a statistically significant improvement was found in all the measured parameters of the social history questionnaire. The pretreatment to follow-up differences on the scales of interpersonal adjustment, abstinence and global adjustment reached a high degree of statistical significance (p < 0.001). A high rating of more than 8 on the 10-point scales measuring global adjustment and drinking behavior was considered an indicator of 'essential rehabilitation'. On the basis of this definition, the number of 'essentially rehabilitated' patients was 22 (46.8 %) in regard to global adjustment, and 25 (53.2 %) in regard to abstinence. A total of 18 patients (38.2 %) remained completely abstinent for the entire 6-month follow-up period.
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