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Gan BK, Baugh D, Liu RH, Walia AS. 
“Simultaneous analysis of amphetamine, methamphetamine, and 3, 4-methylenedioxymethamphetamine (MDMA) in urine samples by solid-phase extraction, derivatization, and gas chromatography/mass spectrometry”. 
J Forensic Sci. 1991;36(5):1331-41.
Abstract
A rapid and effective solid-phase extraction procedure using Bond Elute Certify(TM), bonded silica sorbent cartridges was adopted to extract amphetamine, methamphetamine, and 3,4-methylenedioxymethamphetamine (MDMA or Ecstasy) from urine samples. The extract was derivatized with trichloroacetic anhydride prior to gas chromatography/mass spectrometry (GC/MS) analysis with selected ion monitoring of the following ions: 190, 91,188; 204, 91, 202; 162, 135,202; 194, 123; and 211, 209 for the derivatized amphetamine, Cumiskey, methamphetamine, MDMA, ds-amphetamine, and d,-methamphetamine, respectively. The first of the ions listed for each compound was used for quantitation. The compound ds- amphetamine was used as the internal standard for amphetamine, and dg-methamphetamine was used for methamphetamine and MDMA. Results showed a higher than 65% recovery and a reproducibility with less than a 5% coefficient of variation. When a sample size of 2 was used, the lowest detectable concentration was about 50 ng/mL, and a near-perfect : fit can be obtained (within the 250 to 400(I-ng/mL concentration range studied) using a second-order polynomial model.
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