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Erowid References Database

Abramson HA, Jarvik ME, Hirsch MW. 
“Lysergic acid diethylamide (LSD-25): VII Effect upon two measures of motor performance”. 
J. Psychol.. 1955;39:455.
PROBLEM: The effect of LSD on two tests of hand-eye coordination.

MATERIAL: 12 non-psychotic adults (6 M, 6 F). Age range 21-33. METHODS: ll subjects tested three times at intervals of at least one week. 8 subjects were tested four times. The first and 4th tests were after placebo. Before the 2nd and 3rd test the subjects were given 50 and lOO ug LSD orall_respectively. Tests carried out approxo 2-2 1/2 hours after administration of LSD or placebo.

RESULTS: There were no statistically significant differences between the scores after placebo and after LSD, or between the scores after 50 ug LSD and IO0 ug LSD. The tendency was for increasing impairment of performance with increasing doses. LSD tended to interfere with the normally anticipated improvement under subsequent testing with the same tests. However, some improvement occured despite LSD and this improvement tended to counteract the effect of LSD on test performance.
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