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Tylden E. 
“Problems associated with LSD”. 
Brit. J. Med.. 1968;1:704-705.
Many cannabis smokers are aware that prolonged coma occurs with an excessive intake of this drug. I saw the patient reported by Dr. R. Clayton (20 January, p. 163) shortly before his admission to the hospital, as he was under my care for psychotherapy at University College Hospital. He had begged me to prescribe him tincture of cannabis, as his anxiety was intolerable and he wanted to be "stoned out of his mind all the time for the rest of his life." He refused to consider admission as an inpatient, and agreed to try diazepam. I have seen him since his episode with Dr. Clayton and had his account of what happened.
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