Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
Erowid References Database
Trulson ME, Crisp T. 
“Tolerance Develops To LSD While The Drug Is Exerting Its Maximal Behavioral Effects: Implications For The Neural Bases Of Tolerance”. 
European Journal of Pharmacology. 1983;96:317-320.
Tolerance to a test dose of 50 mg/kg of LSD occurred within 0.5-1.0 h following an initial dose of 10 mg/kg of the drug, using limb flicking and abortive grooming as behavioral indices in the cat. These findings represent an example of very rapidly developing drug tolerance using a behavioral index. These data are discussed within the context of hypotheses concerning the neurochemical bases of tolerance to LSD.
Comments and Responses to this Article
Submit Comment
[ Cite HTML ]