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Nakahara Y, Niwaguchi T, Ishii H. 
“Studies on Lysergic Acid Diethylamide and Related Compounds. VI Steric Requirements of von Braun Reaction”. 
Tetrahedron. 1977;33,(13):1591-93.
A study of the von Braun reaction of stereoisomer of LSD (1) and related compounds is presented. The lysergic and derivatives shown below, prepared from D-lysergic acid (Sigma-Chem.) by standard methods, and agroclavine (Aldrich) were reacted with BrCN/CHCl3 according to the von Braun procedure. No reaction occurred with ( 3), ( 5)

(13), (14), (17) or (18) whilst other compounds afforded the N66 cyano derivatives. IR. UV and MS data are cited.

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