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Burgers ACJ, Leemreis W, Dominiczak T, van Oordt GJ. 
“Inhibition of the secretion of intermedine by d-lysergic acid diethylamide (LSD 25) in the toad, Xenopus laevis”. 
Acta endocrin.. 1958;29:191-200.
LSD causes a marked concentration of pigment in the melanophores of the toad (Xenopus laevis). The extent and duration of this effect are directly proportional to the concentration of LSD. . LSD has no effect on pigment dispersion produced in vitro by corticotrophin (intermedine.) . These findings suggest that LSD does not act directly on the melanophores but indirectly by inhibiting the production and/or secretion of the melanophore hormone.
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