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Haley TJ, Dasgupta SR. 
“Intracerebral injection of lysergic acid diethylamide in conscious dogs and cats.”. 
Univ. of California, Los Angeles, School of Medicine, Atomic Energy Project, Report No. UCLA 393.. 1956.
Intracerebral injection of LSD in dogs (20-140 mcg.) and cats (34-210 mcg.) caused profound activation of the autonomic nervous system, resulting in salivation, retching, micturition and mydriasis with reactive pupils. . In the cats sweating, and hypersensitivity to light, sound and touch were noted. "Sham rage" was not observed, but the animals would attack if continuously irritated. . In the dogs ataxia was observed. . In both cats and dogs LSD induced a fear complex. . The significance of the LSD-induced changes is discussed and the possible brain areas involved in the responses are indicated.
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