Dear Erowid Readers: We're a small nonprofit that runs the top drug information website in the world. We have only 4 staff but serve 12 million users, and have costs like any big website: servers, power, office space, programs, and staff. To protect our independence, we don't run ads or take government funds. If everyone reading this gave $3, our fundraising would be done today. If Erowid is useful to you, take a minute to keep it online and ad-free another year!
Donate by Bitcoin

Erowid References Database

Mayer-Gross W, McAdam W, Walker JW. 
“Psychological and biochemical effects of lysergic acid diethylamide”. 
Nature. 1951;168:827.
The minute dosage required to produce the psychological effect of LSD suggested that the mode of action was due to an anti-enzyme action. Since the only substrate metabolized by the brain cell is glucose, an investigation was made of the effect of LSD on carbohydrate metabolism in vivo. The increase in hexosemonophosphate and glucose suggest there is an increased metabolism of glycogen coupled with a probable block in the breakdown of hexo-semonophosphate. The changes in carbohydrate metabolism observed after the intake of LSD are considered responsible for at least part of the psychological symptoms.
Submit Comment
[ Cite HTML ] Plants & Drugs Mind & Spirit Freedom & Law Arts & Sciences Search About Erowid and Feedback Library & Bookstore Copyrights Memberships noref