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Nixon PJ, Youngson CC, Beese A. 
“Tooth surface loss: does recreational drug use contribute?”. 
Clin Oral Investig. 2000;6(2):128-130.
OBJECTIVE: This pilot study was designed to measure tooth wear in a sample of 13 subjects who regularly use amphetamine-like drugs (Ecstasy, amphetamines) and compare the observed wear with a matched sample of nondrug users.

DESIGN: The two groups, both composed of 13 undergraduate students, were matched for age and sex. Other factors influencing tooth wear were controlled by matching the groups on their responses to a questionnaire asking about recognised common causes of tooth wear. The participants teeth were examined and the degree of wear scored according to a tooth wear index.

RESULTS: Severity of occlusal tooth wear of the lower first molar teeth was significantly greater in the drug user group than in the control group (P< 0.05). No other statistically significant differences between the groups were found. CONCLUSION: Regular use of amphetamine-like drugs could be associated with increased posterior tooth wear.
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