- Avoid taking dimenhydrinate (dramamine) if you are currently taking an MAOI, most commonly found in prescription anti-depressants Nardil (phenelzine), Parnate (tranylcypromine), Marplan (isocarboxazid), Eldepryl (l-deprenyl), Aurorex or Manerix (moclobemide), or in Ayahuasca mixtures which contain harmine or harmaline.
- Dimenhydrinate has anticholinergic properties and should not be used by those with glaucoma (raised pressure in the eye), prostatic hypertrophy (enlargement of prostrate gland), or urinary obstructions.
- The anticholinergic effects of atropine and tricyclic antidepressants may be enhanced by dimenhydrinate.
- Avoid mixing dimenhydrinate with central nervous system depressants such as alcohol, barbiturates, hypnotics, narcotic analgesics, sedatives, and tranqullisers. It may enhance the sedative effect of these substances.
- Do not take this product, unless directed by a doctor, if you have a breathing problem such as emphysema or chronic bronchitis.
- Dimenhydrinate may precipitate seizures in those with epilepsy or who have low seizure thresholds.
- Stop taking dimenhydrinate and seek emergency medical attention if you experience an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).
- The safety of this product for pregnant women has not been determined.