If Anything It Enhanced the Effects Significantly
LSD & Fluoxetine
by ren
Citation:   ren. "If Anything It Enhanced the Effects Significantly: An Experience with LSD & Fluoxetine (exp69000)". Erowid.org. Mar 2, 2021. erowid.org/exp/69000

40 mg oral Pharms - Fluoxetine (daily)
  15 hits oral LSD (blotter / tab)


I have often heard that prozac and ssri's significantly reduce the effects of psychedelics and LSD. I don't find this to be true. Let me begin by saying I do not like acid. Anymore. I used to do it a lot and loved it, as well as other psychedelics and didnt have a problem. A while back I dosed under the wrong mindset and had a horrible, frightening trip. This was probably because I had a very bizarre scary experience with salvia and it kinda put me into a realization that I am not invincible to psychedelics. Since then I have been very cautious of psychedelics. I have used mushrooms countless times since, but I have been reluctant to use LSD since out of fear of having the same bad trip. I have heard that if you have a massively bad trip once, it is impossible to have a good trip as you cannot trick your brain into ignoring the feeling you had during that trip. Before that I had taken large amounts and been fine, better than fine is more like it, as some of the best times (with psychedelics) I've had were on acid. I'm not going to get into the bad trip. I dont even like to remember that day as it makes me uneasy.

But anyway, a few years later, I began selling acid to make a few bucks as it isn't easy to find where I live, and I had a connection, so you know, why not. I wasn't using it myself. I have heard that taking antidepressants, specifically ssri's reduce the effects of psychedelics. Well nowdays I take prozac for depression, though I don't think I really need it anymore. But always having LSD around can get tempting and one day I was drinking with some friends and they were all tripping. Well needless to say I couldnt resist and took a few hits, and then I said screw it and ate a few more, 15 total.

Within 10 or 15 minutes it was comin on pretty strong, alot faster than it had ever kicked in before. Within an hour I was tripping extremely hard and started to get ansty and began to have doubts about it and started thinking maybe I had made a big mistake. I decided to go for a walk to try and relax. Thank god I wasn't having the same feeling from my 'bad' trip but I was extremely uneasy and kinda nervous as to where this trip was going cuz I was really tripping balls and still nowhere near the peak. But the more I walked the more everything seemed not real and messed up. I wasn't sure I could handle the peak cuz after about 2 hours I was already tripping harder than I ever remember tripping before, and had turned inward and began analyzing my life and looking at all the thoughts I have that always go through my head but I dont really notice. I eventually found a little corner by a fence in my neighborhood and just huddled in the snow and went along for the ride, contemplating everything about the futility of everything of my life, wondering what the purpose was, with my thoughts going in repeating loops of such. Also I'd find myself scared about falling into the same bad trip I previously had, but then reassuring myself that even if I did, I had survived it last time, and I never actually did come to the same level of paranoia.
I'd find myself scared about falling into the same bad trip I previously had, but then reassuring myself that even if I did, I had survived it last time, and I never actually did come to the same level of paranoia.

It wasn't really a bad trip, just a sort of uncomfortable one, until I passed my peak and calmed down a bit and went back home. The last 6 or so hours while I was coming down were actually quite enjoyable. On previous occasions, I have taken at least 25 hits of acid. But this was definitely the most intense acid trip I ever experienced, off of 15. Some people say that prozac reduces the effects of LSD and other psychedelics. This was definitely not true for me. If anything it enhanced the effects significantly. There's always the possibility that it was much better acid than I had ever had before, but the feedback from most of my friends who I had been selling it to before that was that it was maybe a little better than average, but nothing significant. But either way the prozac I was on did not reduce the effects of it, as far as I could tell at least. I hadn't taken acid from that batch not on it to compare, but it definitely seemed to enhance the acid for me.

Exp Year: 2007ExpID: 69000
Gender: Male 
Age at time of experience: Not Given 
Published: Mar 2, 2021Views: 159
[ View as PDF (for printing) ] [ View as LaTeX (for geeks) ] [ Switch Colors ]
LSD (2) : Difficult Experiences (5), Combinations (3), Small Group (2-9) (17)

COPYRIGHTS: All reports are copyright Erowid and you agree not to download or analyze the report data without contacting Erowid Center and receiving permission first.
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.

Experience Vaults Index Full List of Substances Search Submit Report User Settings About Main Psychoactive Vaults