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Possibly Reacted Very Badly With My Meds
Ayahuasca, Bupropion & Fluoxetine
by whixbee
Citation:   whixbee. "Possibly Reacted Very Badly With My Meds: An Experience with Ayahuasca, Bupropion & Fluoxetine (exp67289)". Apr 6, 2020.

  oral Pharms - Bupropion (daily)
    oral Pharms - Fluoxetine (daily)
  2 cups oral Ayahuasca (tea)


[Erowid Note: Combining MAOIs with other psychoactive drugs carries serious medical risks and can result in extremely unpleasant side effects, overheating, nausea, confusion, heart problems, and even death. Please see Erowid's MAOI Vault]

Meds.: Prozac, Wellbutrin.
Psych. Condition: Diagnosed with depression, learning disability, anxiety disorder, cognitive disorder.

I ordered the two part ayahuasca mix, which consisted of the Banisteriopsis vine and Psychotria Viridis. After receiving these items, I placed them both in one pot, filled the pot with water, boiled the mix, then allowed the resulting tea to become very condensed, like an extremely strong tea.

Big, BIG MISTAKE! The resulting mix was far too strong and possibly reacted very badly with my meds! The beginning of the effects were so slow in coming, that I drank a second cup of this wretched stuff, not realizing that the peak of the experience would be so very strong and terrifying.
I drank a second cup of this wretched stuff, not realizing that the peak of the experience would be so very strong and terrifying.

One hour into the experience, I thought that I was dying. I felt terrified that I was going to die because of this substance. (I understand that some people have this 'Going to Die' experience, as well.) The beginning was pleasant, AT FIRST. I felt some happiness, or euphoria, empathy and compassion for others (which is odd), and even more oddly, I felt some near orgasmic sexual pleasure! Why the hell did that happen? Each thought, each word caused sexual pleasure for a span of time. Everything in the world seemed to be connected in ways that I had never realized. Everything was interconnected and related. Visually, all of the objects, textures and everything that I could see were much more enhanced: I felt a strong ecstatic 'Whoa, Dude!' fascination towards anything seen. Also, I felt some freedom from my conditioned ingrained pattern of thinking for some strange reason. I felt free of my old thinking, for a while. When I closed my eyes, I could see (hallucinate), the classic spiral fractals that many people see when experiencing LSD trips. For a brief while, I could see, in my mind only, beautiful green leaves of the most perfect green and a flash of a jungle scene. Then I started to see, in my mind only, flashes of insectile fractals, skeletal images and fractals along with the colors red and black.

At this time the trip became more intense and out of control, frightening. I started to think that I was going to die, and felt terrified of my possible death, which is interesting at the time of this writing, as I have felt suicidal in years past. I guess the jokes on me, huh? The terrifying part took forever, time slowed down painfully at this point, and eventually I came down.

The entire experience took about four hours. I couldn't sleep well for two days after this, or I didn't need much sleep after this, I don't know which. There was no depression, the day after, no feeling of demoralization that I felt after a drunken binge --- in fact a slight lifting of my spirits, which is odd for me.

I will make another attempt soon with this Ayahuasca much later, but only after I carefully slowly wean myself from my meds, with a much, much lower concentration. Be warned!

Exp Year: 2007ExpID: 67289
Gender: Male 
Age at time of experience: 47 
Published: Apr 6, 2020Views: 872
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Ayahuasca (8) : Difficult Experiences (5), Therapeutic Intent or Outcome (49), Combinations (3), Unknown Context (20)

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