Citation: Rapkarla. "Disappointment: An Experience with LSD, Sertraline & Bupropion (exp54624)". Erowid.org. Jun 14, 2007. erowid.org/exp/54624
I take 200 mg sertraline and 300 mg bupropion daily for depression. I had read that anti-depressants can lessen the effects of psychedelics such as LSD. I figured that a little trip is better than no trip at all, right?
I took just one tab at first, because I am sensitive in general to psychoactive substances. I was with a very experienced psychonaut friend, R, just hanging out in my apartment. I was a bit nervous because I've landed in the ER with bad drug interactions before and it sucks. But I felt pretty confident that my day wouldn't end in a hospital. R and I watched tv while I waited to feel something. I did feel pretty weird. It felt a little like the body high from a low dose of DXM, with almost none of the mental/emotional intrigue. My neck got very stiff and sore, and I couldn't focus my eyes properly. I had no visual or auditory hallucinations of any kind. The most noticeable aspect was a kind of buzzing feeling in my whole body, like it was antsy and ready to blast off to outer space but couldn't quite make it off the ground. I took a second tab about 4-5 hours after the first one just to see if it was a matter of dosage. It wasn't.
One thing that was mildly interesting: I couldn't taste food. My brain was receiving the information all the same, but I was experiencing it in a way other than tasting, I don't know what exactly. I guess that's a kind of synesthesia, like hearing colors or whatever. I spent most of the 'trip' laying around watching tv and trying to sleep off the neck and jaw stiffness. I couldn't sleep though. Overall a huge disappointment followed by a massive 24-hour headache. I will have to plan very carefully if I want to try to go off the meds for a few days so I can attempt to trip. It's not usually worth it.
COPYRIGHTS: All reports are copyright Erowid and you agree not to download or analyze the report data without contacting Erowid Center and receiving permission first.
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid Center.