DOSE:

50 mg

oral

DiPT

BODY WEIGHT:

150 lb

I weighed 50mg DiPT fumarate and drank it with water. DiPT is known for shifting perceived pitch downwards. The shift happened gradually. In this report, I will mention the musical interval by which I could hear that pitches were lowered by. Without having perfect pitch, I can confidently determine the pitch shift being experienced through this method: I can play a piece of music on the piano, and very distinctly hear whether the starting pitches sound correct or not. If it doesn't sound correct, I transpose the starting pitches until it does. The interval by which I have to transpose the starting pitches up by for it to sound distinctly correct is the interval by which DiPT is shifting my pitch perception downwards

T0:55 Perceived pitch is a minor third beneath actual pitch f*0.84
Very strong tinnitus at a lower frequency than sober tinnitus

T2:09 Perfect fourth beneath actual pitch f*0.75

T3:05 Between a perfect fourth and a tritone beneath actual pitch
Strong high pitched tinnitus

T3:50 Perceived pitch is a major second beneath actual pitch

T4:10 Sine wave generator: Between 20Hz and 30Hz: Extremely faint buzz at the lowest end of my hearing range. 31Hz: I can begin to faintly hear pitches 17000Hz: Audible

I could definitely hear sine waves beneath 31Hz down to around 25Hz much more distinctly while sober. I could not confidently say if there were differences at the upper end.

The factor by which perceived pitch is lowered seems to increase with the amount of DiPT present in the brain, as the pitch becomes lower in the middle of the experience when the DiPT present is expected to be higher, and tapers off towards the beginning and end. The DiPT is obviously not changing which frequencies the hair cells are sensitive to. It is somehow interfering with some sort of signal that happens later into the pathway. Could indicate that somewhere along the auditory stream, there is a signal mediated by serotonin (DiPT mostly affects serotonin receptors) that comes before perceived pitch. If this were the case, higher activation seems to be inversely related with perceived frequency. If this were the case though, we should expect other serotonergic drugs like DMT to similarly cause pitch to be shifted downwards. It would be interesting to see human neuroimaging with DiPT. I'm not sure if there are certain auditory reflexes or responses that are pitch discriminative. If this were the case, we could maybe also figure out which auditory streams DiPT affects the pitch perception for.

This is just speculation from someone who doesn't have a background in science.

The higher register on the piano, and higher pitched sounds are grainy/metallic -> Is it because highest frequencies are all being downshifted, creating a "gap" at the upper end of perception? I don't know too much about audio so I cannot confidently say if this would cause such an auditory effect.

Exp Year: 2025	ExpID: 118874
Gender: Male
Age at time of experience: Not Given
Published: Dec 20, 2025	Views: Not Supported
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DiPT (110) : Music Discussion (22), General (1), Alone (16)