DOSE:	100 - 300 mg	oral	Pharms - Gabapentin
	10 mg	oral	Pharms - Propranolol
	15 mg	oral	Cannabidiol

BODY WEIGHT:

140 lb

I’ve never had issues with anxiety—depression, yes; anxiety, never—until about a year and a half ago, when I suddenly started having panic attacks out of nowhere. CBD in the form of liquid tinctures (~15mg/dose) helped calm me down for short periods, but it wasn’t enough. So my doc prescribed me Gabapentin, and it’s been an absolute miracle.

I take a 300mg pill and after about 45 min, feel myself starting to relax. An hour later, the anxiety is seeping away, the thoughts are calming down, and by 1.5 – 2hrs, I’m feeling great; it’s basically like being tipsy. Peak effects 4-6 hrs; benefits still at 8 hrs.
• I get much more social and talkative—which as an introvert who works with a lot of extroverts, is VERY handy!
• My inhibitions come down (gotta watch what I say, though, lol!)
• I’m able to focus much better on whatever I’m doing (which makes it great for getting shit done)
• I have far more bandwidth for situations that would normally burn me out fast (crowds, noise, managing annoyances/irritations, etc.)
• Fear/anxiety is mostly absent
• Physical sensations become more pleasant…and though climax is harder to reach, holy crap is it worth it!!

HOWEVER. Even with that, when my anxiety was at its worst, I could still sometimes feel the spikes of adrenaline of the fear trying to come out. My mind was calm, but my body was not, and while it was manageable, it was not pleasant. 300mg Gabapentin also made me more stoned than I wanted to be for daily functioning, so I wanted to try a lower dose. So my doc prescribed 100mg Gabapentin in addition to the 300mg, and 10mg Propranolol.

The Propranolol has been another life-saver. I didn’t realize how intensely I was experiencing the physical effects of anxiety until they were gone. It basically blocks the effect of adrenaline. Effects start to kick in w/in 15 min, and w/in an hour it’s at full strength. When I take one, I KNOW it’s basically IMPOSSIBLE for me to have a panic attack for the next 4-6 hours—and that thought alone significantly reduces my anxiety. The thoughts may race, but the body won’t freak—because it literally can’t. The only negative effect is that it makes exercise feel harder, but I just push through it and do what I can.

The combo of Propranolol for the body, PLUS Gabapentin for the mind, has given me my life back.

The 100mg Gabapentin has also been a pleasant surprise. My long-term goal is to get off all anti-anxiety meds, and as I’ve been recovering, I’ve been experimenting with taking 200mg G, then just 100. Nowadays, 100mg is as effective as 300 used to be, and gives the other good benefits w/out making me feel stoned. It’s a good balance.

Other notes:
• 300mg Gabapentin (especially + 15mg CBD tincture) is an excellent substitute for alcohol, and is also great for a good night's sleep--especially before a stressful day.
• I’m ok to drive at these doses of Gabapentin, but find myself less attentive w/ CBD on board, so I try to avoid CBD when driving. Sometimes I’ll mix a few ounces of a CBD beverage in w/ my water, and that’s safe to sip on.
• I once tried 600mg G just for fun, and was stoned out of my brain for a few hours. It was not unpleasant, but not something I have any desire to do again.

Exp Year: 2025	ExpID: 118781
Gender: Female
Age at time of experience: 47
Published: Jul 19, 2025	Views: Not Supported
[ View PDF (to print) ] [ View LaTeX (for geeks) ] [ Swap Dark/Light ]
Pharms - Propranolol (72), Cannabidiol (596), Pharms - Gabapentin (183) : Various (28), Therapeutic Intent or Outcome (49), Medical Use (47), Glowing Experiences (4), Combinations (3)