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Dangerous and Stupid Will Robinson...
DMT, Trazodone & Melatonin
Citation:   TweekBoy. "Dangerous and Stupid Will Robinson...: An Experience with DMT, Trazodone & Melatonin (exp118234)". Erowid.org. Nov 5, 2025. erowid.org/exp/118234

 
DOSE:
T+ 0:00
2600 mg oral Acetaminophen
  T+ 0:00 12 oz oral Alcohol - Beer/Wine
  T+ 2:30 1300 mg oral Acetaminophen
  T+ 2:30 100 mg oral Pharms - Trazodone
  T+ 2:30 30 mg oral Melatonin
  T+ 0:00   vaporized DMT
BODY WEIGHT: 155 lb
DMT, Trazadone, Melatonin, Sierra Nevada Pale Ale, Tylenol

First off, I know I’m an idiot for the combo. I’ve been using psychedelics for 33 years and have no idea how I got to this combo of stupidity justified in my head last night.

I started with 4 Tylenol Arthritis or 2,600mg and a beer with dinner at around 7pm. I’ve never had issues in the past with mixing Tylenol, low dose alcohol, and vaping DMT. Then around 9:30 I took 1,300 more of Tylenol and sleep meds of 100mg of Trazadone and 30mg of Melatonin.

I NEVER in 33 years have taken a drug like Trazadone within 5 days of vaping DMT or use of any psychedelic substance. If my sleep is off, I’ll take Trazadone and Melatonin, but I ALWAYS in the past gave myself the higher end of half life estimates and waited to use psychedelics until Trazadone was totally out of my system.
I ALWAYS in the past gave myself the higher end of half life estimates and waited to use psychedelics until Trazadone was totally out of my system.


This wasn’t the case last night. I think it was just that Trazadone stupor I get if I don’t take it everyday that led me to grab my vape pen with DMT. I make my own carts and always have. 1:1 ratio. I do however do my carts at 650mg of DMT to .65ml of straight PG and fills them to the brim. I’m precise. I live and die to study psychedelics.

So I took my normal full 10sec rip off my pen plus a little extra and had a very non visual trip. To be expected I thought with Trazadone. No big deal. Or so I thought. About an hour after DMT was done I went to make a fruit smoothie and apparently blacked out. I woke up tangled in my bike that is in my room. Nearly sent my bike into my guitar, but instead took out my router thank God. But I have no memory today. Gone? My head is very “full” feeling today like a cross between a cold and tail end of nitrous high. I’m functional today, but way way off. Daffy almost?

Long story short, no go I’d say on Trazadone and psychedelics.

Exp Year: 2024ExpID: 118234
Gender: Male 
Age at time of experience: 48
Published: Nov 5, 2025Views: Not Supported
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DMT (18), Pharms - Trazodone (294) : Alone (16), Hangover / Days After (46), Train Wrecks & Trip Disasters (7), Combinations (3)

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