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A Fascinating Synergy
Huasca Combo (Syrian Rue, Passion Flower & Mimosa tenuiflora) & Calea zacatechichi
Citation:   joukahainen. "A Fascinating Synergy: An Experience with Huasca Combo (Syrian Rue, Passion Flower & Mimosa tenuiflora) & Calea zacatechichi (exp115820)". Oct 14, 2021.

T+ 0:00
800 - 1000 mg oral Syrian Rue (tea)
  T+ 0:45 400 - 500 mg oral Syrian Rue (tea)
  T+ 0:45 2.5 g   Mimosa tenuiflora (rootbark)
  T+ 0:45     Passion Flower (tea)
  T+ 2:15 400 - 500 mg oral Syrian Rue (tea)
  T+ 2:15 2.5 g   Mimosa tenuiflora (rootbark)
  T+ 2:15     Passion Flower (tea)
  T+ 2:15   buccal Calea zacatechichi (dried)
Discovered a fascinating synergy between Calea Zacatechichi and Ayahuasca. This experience has been repeated multiple times and is becoming somewhat of a ritual for me. The basic components required are Ayahuasca and dried leaves of Calea dreamherb.


- concentrated (triple-boiled in acidic water and reduced) tea of Mimosa Hostilis rootbark: dose equivalent to 5 grams rootbark

- concentrated tea of Syrian Rue (Peganum Harmala) seeds: dose equivalent to 1.6 - 2.0 grams seeds

- a few pinchfuls of Calea dreamherb, dried

- Passionflower tea (Passiflora Incarnata), simmered for an hour at 90 degrees Centigrade

The passionflower tea is not required nor does it seem to affect the experience at all. It's a nice-tasting base liquid into which the other drinkable components are mixed. The ayahuasca components could be substituted with other similar plants but I have only tried this with MHRB and Syrian Rue. I usually prepare the concentrates such that the volumes ingested are easily manageable, preferrably fitting in a shotglass. The amount of Syrian Rue I require in Ayahuasca is very small. The small doses have the benefit of little to no gastrointestinal upset. I have never purged at these doses.

Timeline of events:

I chug half of the Syrian Rue tea as-is. This is to have some MAO inhibition before ingesting any of the DMT.

I mix the remaining half of Syrian Rue tea along with all of the MHRB tea into a large glass or pint. I fill the remaining volume with still hot Passionflower tea. Having such a large liquid volume allows me to more easily control the initial rate of ascent.

At this point I usually lay down, stretch, listen to music, small meditative practices to clear my mind.

Sometimes I feel the Syrian Rue, sometimes not. The effect from such a small dose is very subtle.

I start sipping from the pint. At this stage I will consume up to half of the liquid, conserving the rest for the next phase.


Start feeling the first effects from MHRB. Since the dosage is quite low and the rate of ingestion slow, the comeup is usually fairly gentle. I continue sipping the combined tea at a pace I'm comfortable with. Sometimes it's harder to let myself go, other times my mind is like flowing water and welcomes the experience.

Either way, nothing groundbreaking happens at this stage. After consuming up to half of the combined tea I enjoy the rest of the comeup and wait for the moment I start coming down. It's very hard to tell how much time has elapsed but I'd estimate this is typically at T+02:00.

I linger here for a little bit longer. At this point I have completely shed my everyday thoughts and I'm very comfortable with the experience and ready to lose myself.


I chug the remaining tea. In this state of mind it goes down easily.

I completely fill my upper lip with dry Calea, packing the mass tighter with my tongue. The same way one might use tobacco dip/snus.

I turn off all the lights and lay down alone in a comfortable bed.

I put on headphones and always play the same album: World of Sleepers by Carbon based lifeforms.

Giggling like a lunatic I wait for liftoff.

First I start feeling the Calea. It has a very bitter taste when taken sober but in this synergistic state I don't really taste it at all. I feel it more as this kind of fuzzy hairiness. The feeling begins in my upper lip but as the mass gets moist from saliva it starts getting absorbed. The fuzzy hairiness spreads to the surrounding parts of my face. Then it hits the brain.

The first effects are on closed eye visuals which are overtaken by these tentacles consisting of lines of fuzzy pyramids. It completely transforms the Aya visuals into more distinct, very bizarre cartoonish, artistic images. Some kind of hypnagogic imagery going on here.

Next I feel it taking over my mind. The first time this happened I instinctively spat out the Calea. The nice thing about sublingual absorption is that it's very easy to abort if you get cold feet. The effect is very hard to put into words. There might be a spinning feeling involved along with those fuzzy pyramids poking me all over my existence (no longer aware of my body).

There is usually a sense of transitioning to a distinct "space", the Calea dreamspace. It's very tranquil and filled to the brim with artistic creativity. I've seen some wonderful things there. Some could even be somewhat described by words but what would be the point.

At this point the Calea absorbtion is probably still picking up pace and the second Aya dose starts taking effect. I'm completely lost in this new space but this is just the beginning.

What happens next could be best described as psychedelic overload. Everything in this space comes to life and starts doing its own thing. Everything fuses together. The music is no longer music, it's the whole existence, there is nothing outside it as there is no "outside it". There is no longer any fear as there is no longer an I. All there is is experience. Drifting through cavernous spaces consisting of pure psychedelia.

This overwhelming psychedelic attack slowly erodes all that is left of my mind. As this happens the psychedelia is also subdued and I'm left floating in a formless warm-colored space.

There is no longer any form. This is a formless experience.

I experience myself react to stimuli (the music is still playing). I have no symbol table, everything is completely abstract but I still process the stimuli and make memories of them. Maybe at some later time these memories will be useful?

This formless state is a source of boundless creativity. When form begins to appear the epiphanies start. The first one is always the same: this is the state of an unborn mind. From this complete abstraction we build our minds. Before this there is only pure formless experience.

I can see through the layers of learned behavior. Peel them away at will. I access memories I didn't know I still had. I recall key moments from building my own consciousness as a child. I think of my own children doing the same. A lot of thoughts related to personal issues often arise. Another time I look deeper into this formless mind and see the biology behind it. I become aware of its mindboggling complexity arising from billions of years of evolution. I become aware of the scale of life. I experience life as a chaotic intertwined tree-like mass covering the whole planet with roots so far back in time that I cannot even perceive it and with an even longer future. I become aware that "I" am just one small leaf in that tree, trapped between the immeasurable past and the vast future. I see my everyday self as just another biological process guided by evolution's programming. I can look at my behaviors and wonder what purpose they might serve or once served. I'm struck by the realization that I along with all other humans are life's instrument of introspection. For the first time in 3.9 billion years life has a way of looking at itself. It has evolved a consciousness. There is a wonderful sense of oneness with all life past, present and future.

These epiphanies leave me lying awestruck in a state of absolute bliss. These are not a one-off occurrence, I've come to expect them each time doing this ritual which I've repeated three times by now. The combined effects from Calea and the second Aya dose have so far always followed the same pattern of initial physical and mental effects, transitioning to the Calea space, an overwhelming psychedelic attack and slowly being reduced to a formless experience. Rebuilding form seems to be a great opportunity for higher/altered perspectives on things and overall creativity. Every time I've come back with insights I didn't have going in.

The Calea space is definitely distinct from the Aya space experienced at this dose. In fact I can "sink" back to the Aya space in a minute or two by simply removing the Calea from my mouth.

Exp Year: 2021ExpID: 115820
Gender: Male 
Age at time of experience: 35
Published: Oct 14, 2021Views: 1,735
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Huasca Combo (269), Calea zacatechichi (97), Syrian Rue (45), Mimosa tenuiflora (74), Passion Flower (121) : Combinations (3), Glowing Experiences (4), Preparation / Recipes (30), Alone (16)

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