Erowid
 
 
Plants - Drugs Mind - Spirit Freedom - Law Arts - Culture Library  
It's Erowid's 20th Anniversary!
Help us keep going for another twenty with a small donation?
Erowid is a global information resource. We're an educational non-profit working to provide an honest look at psychoactives. Accurate info is required in order to move forward with research, drug law reform, and safer use. This work is made possible by small donations and memberships (get our newsletter!).
Desomorphine (Krokodil) Chemistry
by Erowid



NAME :Desomorphine (Krokodil)
CHEMICAL NAME :4,5a-epoxy-17-methylmorphinan-3-ol
ALTERNATE CHEMICAL NAMES :dihydrodesoxymorphine-D;
CHEMICAL FORMULAC17H21NO2
MOLECULAR WEIGHT271.36
MELTING POINT162-164° C (Hemihydrate, from ethyl acetate);
232° Hydrogen sulfate dihydrate browns at 210C and is unmelted at 230C


Desomorphine molecule


From the Merck Index 12th Edition

2972. Desomorphine. 4,5a-Epoxy-17-methylmorphinan-3-ol; dihydrodesoxymorphine-D; Permonid. C17H21N02; mol wt 271.36. C 75.25%. H 7.80%. N 5.16%. O 11.79%. Synthesis. physical data: L. F. Small et al., J. Am. Chern. Soc. 55, 3863 (1933).

Rectangular plates from acetone-water. Sublimes in high vacuum between 140C and 170C. (Anhydr base mp 189C). [alpha]28/D - 77C (c = 1.6 in methanol). Sol in acetone. ethyl acetate. Alcoholic solns darken and acquire a reddish color.

Hemihydrate, crystals from ethyl acetate. mp 162-164C. [alpha]28/D - 79C (c = 1.08 in ethyl acetate).

Hydrochloride. C17H21N02.HCl, crystals from alcohol. [alpha]27/D -67C (c = 0.90). Very soluble in water.

Hydrogen sulfate dihydrate. (C17H21N02)2.H2S04.2H20. scales. plates from water, brown at 210C, unmelted at 230C. Sol in 40 parts water; freely sol in hot water. Soln is stable to boiling. [alpha]29/D - 60C (c = 1.43).

Note: This is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations. Title 21 Part 1308. II (J 995). THERAP CAT: Analgesic (narcotic).