|NAME :||Desomorphine (Krokodil)|
|CHEMICAL NAME :||4,5a-epoxy-17-methylmorphinan-3-ol|
|ALTERNATE CHEMICAL NAMES :||dihydrodesoxymorphine-D;|
|MELTING POINT||162-164° C (Hemihydrate, from ethyl acetate);|
232° Hydrogen sulfate dihydrate browns at 210C and is unmelted at 230C
From the Merck Index 12th Edition
2972. Desomorphine. 4,5a-Epoxy-17-methylmorphinan-3-ol; dihydrodesoxymorphine-D; Permonid. C17H21N02; mol wt 271.36. C 75.25%. H 7.80%. N 5.16%. O 11.79%. Synthesis. physical data: L. F. Small et al., J. Am. Chern. Soc. 55, 3863 (1933).
Rectangular plates from acetone-water. Sublimes in high vacuum between 140C and 170C. (Anhydr base mp 189C). [alpha]28/D - 77C (c = 1.6 in methanol). Sol in acetone. ethyl acetate. Alcoholic solns darken and acquire a reddish color.
Hemihydrate, crystals from ethyl acetate. mp 162-164C. [alpha]28/D - 79C (c = 1.08 in ethyl acetate).
Hydrochloride. C17H21N02.HCl, crystals from alcohol. [alpha]27/D -67C (c = 0.90). Very soluble in water.
Hydrogen sulfate dihydrate. (C17H21N02)2.H2S04.2H20. scales. plates from water, brown at 210C, unmelted at 230C. Sol in 40 parts water; freely sol in hot water. Soln is stable to boiling. [alpha]29/D - 60C (c = 1.43).
Note: This is a controlled substance (opium derivative) listed in the U.S. Code of Federal Regulations. Title 21 Part 1308. II (J 995). THERAP CAT: Analgesic (narcotic).