Isopropyl Alcohol Material Safety Data Sheet
Common Name: Isopropyl Alcohol CAS Number: 67-63-0 DOT Number: UN 1219 Date: September, 1988
HAZARD SUMMARY * Isopropyl Alcohol can affect you when breathed in and by passing through your skin. * There is an increased risk of cancer associated with the manufacturing of Isopropyl Alcohol. * Exposure can cause irritation of the eyes, nose, mouth, and throat. * Overexposure may cause headaches, drowsiness, clumsiness, unconsciousness, and death. * Contact may irritate the skin. Repeated skin exposure can cause itching, a rash, and drying and cracking. * Isopropyl Alcohol is a FLAMMABLE LIQUID and a FIRE HAZARD. IDENTIFICATION Isopropyl Alcohol is a colorless liquid. Rubbing alcohol is a solution of Isopropyl Alcohol. It is used as a solvent and in making many commercial products. REASON FOR CITATION * Isopropyl Alcohol is on the Hazardous Substance List because it is regulated by OSHA and cited by ACGIH, DOT, NFPA and EPA. * This chemical is on the Special Health Hazard Substance List because it is FLAMMABLE. * Definitions are attached. HOW TO DETERMINE IF YOU ARE BEING EXPOSED * Exposure to hazardous substances should be routinely evaluated. This may include collecting air samples. Under OSHA 1910.20, you have a legal right to obtain copies of sampling results from your employer. If you think you are experiencing any work related health problems, see a doctor trained to recognize occupational diseases. Take this Fact Sheet with you. * ODOR THRESHOLD = 22 ppm. * The odor threshold only serves as a warning of exposure. Not smelling it does not mean you are not being exposed. WORKPLACE EXPOSURE LIMITS OSHA: The legal airborne permissible exposure limit (PEL) is 400 ppm averaged over an 8 hour workshift. NIOSH: The recommended airborne exposure limit is 400 ppm averaged over a 10 hour workshift and 800 ppm, not to be exceeded during any 15 minute work period. ACGIH: The recommended airborne exposure limit is 400 ppm averaged over an 8 hour workshift and 500 ppm as a STEL (short term exposure limit). * The above exposure limits are for air levels only. When skin contact also occurs, you may be overexposed, even though air levels are less than the limits listed above. WAYS OF REDUCING EXPOSURE * Where possible, enclose operations and use local exhaust ventilation at the site of chemical release. If local exhaust ventilation or enclosure is not used, respirators should be worn. * Wear protective work clothing. * Wash thoroughly immediately after exposure to Isopropyl Alcohol and at the end of the workshift. * Post hazard and warning information in the work area. In addition, as part of an ongoing education and training effort, communicate all information on the health and safety hazards of Isopropyl Alcohol to potentially exposed workers. This Fact Sheet is a summary source of information of all potential and most severe health hazards that may result from exposure. Duration of exposure, concentration of the substance and other factors will affect your susceptibility to any of the potential effects described below. ------------------------------------------ HEALTH HAZARD INFORMATION Acute Health Effects The following acute (short term) health effects may occur immediately or shortly after exposure to Isopropyl Alcohol: * It may irritate the skin, causing a rash or burning feeling on contact. * Exposure can irritate the eyes, nose, and throat. * Overexposure to the vapor may cause headaches, drowsiness, a loss of coordination, collapse, and death. Chronic Health Effects The following chronic (long term) health effects can occur at some time after exposure to Isopropyl Alcohol and can last for months or years: Cancer Hazard * There is an increased incidence of nasal sinus cancer in workers involved in the manufacture of Isopropyl Alcohol by the strong acid process. There is no evidence that Isopropyl Alcohol is a carcinogen. Reproductive Hazard * According to the information presently available to the New Jersey Department of Health, Isopropyl Alcohol has not been tested for its ability to adversely affect reproduction. Other Long Term Effects * Skin exposure can cause itching, redness, and rashes in some people. Repeated or prolonged exposure can cause dryness and cracking of skin. * This chemical has not been adequately evaluated to determine whether brain or other nerve damage could occur with repeated exposure. However, many solvents and other petroleum based chemicals have been shown to cause such damage. Effects may include reduced memory and concentration, personality changes (withdrawal, irritability), fatigue, sleep disturbances, reduced coordination, and/or effects on nerves supplying internal organs (autonomic nerves) and/or nerves to the arms and legs (weakness, "pins and needles"). MEDICAL TESTING * There is no special test for this chemical. However, if illness occurs or overexposure is suspected, medical attention is recommended. * Interview for brain effects, including recent memory, mood (irritability, withdrawal), concentration, headaches, malaise and altered sleep patterns. Consider cerebellar, autonomic and peripheral nervous system evaluation. Positive and borderline individuals should be referred for neuropsychological testing. Any evaluation should include a careful history of past and present symptoms with an exam. Medical tests that look for damage already done are not a substitute for controlling exposure. Request copies of your medical testing. You have a legal right to this information under OSHA 1910.20. WORKPLACE CONTROLS AND PRACTICES Unless a less toxic chemical can be substituted for a hazardous substance, ENGINEERING CONTROLS are the most effective way of reducing exposure. The best protection is to enclose operations and/or provide local exhaust ventilation at the site of chemical release. Isolating operations can also reduce exposure. Using respirators or protective equipment is less effective than the controls mentioned above, but is sometimes necessary. In evaluating the controls present in your workplace, consider: (1) how hazardous the substance is, (2) how much of the substance is released into the workplace and (3) whether harmful skin or eye contact could occur. Special controls should be in place for highly toxic chemicals or when significant skin, eye, or breathing exposures are possible. In addition, the following controls are recommended: * Where possible, automatically pump liquid Isopropyl Alcohol from drums or other storage containers to process containers. * Specific engineering controls are recommended for this chemical by NIOSH. Refer to the NIOSH criteria document: Isopropyl Alcohol #76 142. Good WORK PRACTICES can help to reduce hazardous exposures. The following work practices are recommended: * Workers whose clothing has been contaminated by Isopropyl Alcohol should change into clean clothing promptly. * Contaminated work clothes should be laundered by individuals who have been informed of the hazards of exposure to Isopropyl Alcohol. * On skin contact with Isopropyl Alcohol, immediately wash or shower to remove the chemical. At the end of the workshift, wash any areas of the body that may have contacted Isopropyl Alcohol, whether or not known skin contact has occurred. * Do not eat, smoke, or drink where Isopropyl Alcohol is handled, processed, or stored, since the chemical can be swallowed. Wash hands carefully before eating or smoking. PERSONAL PROTECTIVE EQUIPMENT WORKPLACE CONTROLS ARE BETTER THAN PERSONAL PROTECTIVE EQUIPMENT. However, for some jobs (such as outside work, confined space entry, jobs done only once in a while, or jobs done while workplace controls are being installed), personal protective equipment may be appropriate. The following recommendations are only guidelines and may not apply to every situation. Clothing * Avoid skin contact with Isopropyl Alcohol. Wear solvent resistant gloves and clothing. Safety equipment suppliers/ manufacturers can provide recommendations on the most protective glove/ clothing material for your operation. * All protective clothing (suits, gloves, footwear, headgear) should be clean, available each day, and put on before work. * ACGIH recommends natural rubber, neoprene, nitrile, or polyvinyl chloride protective material. Eye Protection * Wear splash proof chemical goggles and face shield when working with liquid, unless full facepiece respiratory protection is worn. Respiratory Protection IMPROPER USE OF RESPIRATORS IS DANGEROUS. Such equipment should only be used if the employer has a written program that takes into account workplace conditions, requirements for worker training, respirator fit testing and medical exams, as described in OSHA 1910.134. * Where the potential exists for exposures near or over 400 ppm, use a MSHA/ NIOSH approved respirator with an organic vapor cartridge/canister. More protection is provided by a full facepiece respirator than by a half mask respirator, and even greater protection is provided by a powered air purifying respirator. * If while wearing a filter, cartridge or canister respirator, you can smell, taste, or otherwise detect Isopropyl Alcohol, or in the case of a full face piece respirator you experience eye irritation, leave the area immediately. Check to make sure the respirator to face seal is still good. If it is, replace the filter, cartridge, or canister. If the seal is no longer good, you may need a new respirator. * Be sure to consider all potential exposures in your workplace. You may need a combination of filters, prefilters, cartridges, or canisters to protect against different forms of a chemical (such as vapor and mist) or against a mixture of chemicals. * Where the potential for higher exposures exists, use a MSHA/NIOSH approved supplied air respirator with a full facepiece operated in the positive pressure mode or with a full facepiece, hood, or helmet in the continuous flow mode, or use a MSHA/NIOSH approved self contained breathing apparatus with a full facepiece operated in pressure demand or other positive pressure mode. * Exposure to 20,000 ppm is immediately dangerous to life and health. If the possibility of exposures above 20,000 ppm exists, use a MSHA/NIOSH approved self contained breathing apparatus with a full facepiece operated in continuous flow or other positive pressure mode. HANDLING AND STORAGE * Prior to working with Isopropyl Alcohol you should be trained on its proper handling and storage. * Isopropyl Alcohol must be stored to avoid contact with STRONG OXIDIZERS (such as CHLORINE, BROMINE, and FLUORINE) since violent reactions occur. * Store in tightly closed containers in a cool, well ventilated area away from HEAT. * Sources of ignition, such as smoking and open flames, are prohibited where Isopropyl Alcohol is used, handled, or stored in a manner that could create a potential fire or explosion hazard. * Metal containers involving the transfer of 5 gallons or more of Isopropyl Alcohol should be grounded and bonded. Drums must be equipped with self closing valves, pressure vacuum bungs, and flame arresters. * Use only non sparking tools and equipment, especially when opening and closing containers of Isopropyl Alcohol. Common Name: Isopropyl Alcohol DOT Number: UN 1219 DOT Emergency Guide code: 26 CAS Number: 67-63-0 ---------------------------------------- Hazard rating NJ DOH NFPA FLAMMABILITY - 3 REACTIVITY - 0 ---------------------------------------- POISONOUS GASES ARE PRODUCED IN FIRE CONTAINERS MAY EXPLODE IN FIRE ---------------------------------------- Hazard Rating Key: 0=minimal; 1=slight; 2=moderate; 3=serious; 4=severe FIRE HAZARDS * Isopropyl Alcohol is a FLAMMABLE LIQUID. * Vapors may travel to a source of ignition and flash back. * CONTAINERS MAY EXPLODE IN FIRE. * Use dry chemical, CO2, water spray, or alcohol foam extinguishers. * POISONOUS GASES ARE PRODUCED IN FIRE. * If employees are expected to fight fires, they must be trained and equipped as stated in OSHA 1910.156. SPILLS AND EMERGENCIES If Isopropyl Alcohol is spilled or leaked, take the following steps: * Restrict persons not wearing protective equipment from area of spill or leak until cleanup is complete. * Remove all ignition sources. * Ventilate area of spill or leak. * Absorb liquids in vermiculite, dry sand, earth, or a similar material and deposit in sealed containers. * Keep Isopropyl Alcohol out of a confined space, such as a sewer, because of the possibility of an explosion, unless the sewer is designed to prevent the buildup of explosive concentrations. * It may be necessary to contain and dispose of Isopropyl Alcohol as a HAZARDOUS WASTE. Contact your Department of Environmental Protection (DEP) or your regional office of the federal Environmental Protection Agency (EPA) for specific recommendations. ====================================== FOR LARGE SPILLS AND FIRES immediately call your fire department. ====================================== FIRST AID POISON INFORMATION Eye Contact * Immediately flush with large amounts of water for at least 15 minutes, occasionally lifting upper and lower lids. Skin Contact * Quickly remove contaminated clothing. Immediately wash contaminated skin with large amounts of water. Breathing * Remove the person from exposure. * Begin rescue breathing if breathing has stopped and CPR if heart action has stopped. * Transfer promptly to a medical facility. PHYSICAL DATA Vapor Pressure: 33 mm Hg at 68oF (20oC) Flash Point: 53oF (11.6oC) Water Solubility: Miscible OTHER COMMONLY USED NAMES Chemical Name: 2-Propanol Other Names and Formulations: Rubbing Alcohol; Dimethylcarbinol; Isopro panol; sec-Propyl Alcohol. ------------------------------------------ Not intended to be copied and sold for commercial purposes. ------------------------------------------ NEW JERSEY DEPARTMENT OF HEALTH Right to Know Program CN 368, Trenton, NJ 08625 0368 ------------------------------------------ ------------------------------------------ ECOLOGICAL INFORMATION Isopropyl alcohol is a clear, flammable liquid with numerous uses. It is used in antifreeze; as a solvent for gums, shellac and essential oils; in quick-drying inks and oils; in cosmetics such as body rubs, hand lotions and after-shave lotions; and to make other chemicals. It may enter the environment from industrial discharges, municipal waste water treatment discharges, or spills. ACUTE (SHORT-TERM) ECOLOGICAL EFFECTS Acute toxic effects may include the death of animals, birds, or fish, and death or low growth rate in plants. Acute effects are seen two to four days after animals or plants come in contact with a toxic chemical substance. Isopropyl alcohol has slight toxicity to aquatic life. Insufficient data are available to evaluate or predict the short- term effects of isopropyl alcohol to plants, birds, or land animals. CHRONIC (LONG-TERM) ECOLOGICAL EFFECTS Chronic toxic effects may include shortened lifespan, reproductive problems, lower fertility, and changes in appearance or behavior. Chronic effects can be seen long after first exposure(s) to a toxic chemical. Isopropyl alcohol has slight chronic toxicity to aquatic organisms. Insufficient data are available to evaluate or predict the long- term effects of isopropyl alcohol to plants, birds, or land animals. WATER SOLUBILITY Isopropyl alcohol is highly soluble in water. Concentrations of 1,000 milligrams and more will mix with a liter of water. DISTRIBUTION AND PERSISTENCE IN THE ENVIRONMENT Isopropyl alcohol is slightly persistent in water, with a half-life of between 2 to 20 days. The half-life of a pollutant is the amount of time it takes for one-half of the chemical to be degraded. About 77.5% of isopropyl alchohol will eventually end up in water; the rest will end up in the air. BIOACCUMULATION IN AQUATIC ORGANISMS Some substances increase in concentration, or bioaccumulate, in living oranisms as they breathe contaminated air, drink contaminated water, or eat contaminated food. These chemicals can become concentrated in the tissues and internal organs of animals and humans. The concentration of isopropyl alcohol found in fish tissues is expected to be about the same as the average concentration of isopropyl alcohol in the water from which the fish was taken. SUPPORT DOCUMENT: AQUIRE Database, ERL-Duluth, U.S. EPA, Phytotox.