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25I-NBOMe (2C-I-NBOMe)
by Erowid
Caution :   Reactions and experiences may vary dramatically from person to person. [see below]
2C-I-NBOMe Duration
Sublingual / Buccal
( tentative )
Total Duration
6 - 10 hrs
15 - 120 mins
Coming Up
30 - 120 mins
2 - 4 hrs
Coming Down
1 - 4 hrs
After Effects
1 - 7 days
Hangover / Day After
2C-I-NBOMe Duration
( tentative )
Total Duration
4 - 6 hrs
5 - 10 mins
Coming Up
10 - 30 mins
60 - 120 mins
Coming Down
120 - 180 mins
After Effects
1 - 7 days
Hangover / Day After
  • strong open and closed eye visuals, including trails, color shifts, brightening, etc.
  • mood lift, euphoria
  • mental and physical stimulation
  • increase in associative & creative thinking
  • increased awareness & appreciation of music
  • life-changing spiritual experiences
  • erotic, sexual thoughts and sensations
  • feelings of love and empathy
  • psychedelic ideation, grand insights, big ideas
  • general change in consciousness
  • pupil dilation
  • difficulty focusing
  • unusual body sensations (facial flushing, chills, goosebumps, body energy)
  • change in perception of time, time dilation
  • slight increase in heart rate
  • yawning, especially when coming up
  • does not suppress appetite at low doses
  • visual strobing
    (likelihood of negative side effects increases with higher doses)
  • confusion, delirium
  • looping, recursive, out of control thinking ('racing throughts')
  • scrambled communication
  • nausea
  • insomnia
  • paranoia, fear, and panic
  • unwanted and overwhelming feelings
  • unwanted life-changing spiritual experiences
  • tachycardia, hypertension
  • overheating, hyperthermia
  • serotonin syndrome
  • vasoconstriction, peripheral numbness, swelling of feet, hands, face
  • shaking, clenching, dystonia, clonus, muscle spasms, seizure
  • rhabdomyolysis (Gee et al.)
General Effects Notes
2C-I-NBOMe shares some chemical structural similarity to 2C-I and is a very potent 5HT2A agonist with active doses under 1 milligram (1000 ug). Its effects have been compared to 2C-I, LSD, and DOI. There are some reports that effects can be very unpredictable, even with the same person taking the same dose at different times.

Surprisingly, many reports state that 2C-I-NBOMe does not suppress appetite, cause dry mouth, or make food taste too strange to ingest. Appetite suppression is common on euphoriants and psychedelics and 2C-I-NBOMe seems distinct from LSD, DOI, and 2C-I in this regard.

There have been several reports of users of 25C-NBOMe and 25I-NBOMe experienced peripheral vasocontriction that required medical attention. Symptoms begin with tingling, coldness, bluing, and numbness in the fingers, toes, lips, nose, and other extremities. Swelling in the hands, feet, and face have been reported. One user reported numbness lasting more than a week after use.

Addiction and Compulsive Use
Though some reports mention that re-dosing is possible, its duration and psychedelic qualities make compulsive use seem unlikely. However, because its use is so new and uncommon, no definitive statements about it can yet be made.

[750 ug, sublingal] "I was laughing hysterically at everything R is saying, and vise versa. The OEV's/CEV's are incredibly intricate an unavoidable. Definitely an incredibly detailed and layered fractal pattern. I am most certainly in a profound psychedelic headspace (i.e. I intuitively understand the universe, society, etc.) [...] It's much more of a pure psychedelic than it's non-benzyl substituted cousin 2C-I, while still retaining some of the entactogen qualities." -- Exp 93342
[500-1000 ug, smoked] "The lack of mind-fuck makes it easier to deal with how incredibly high I instantly get when I freebase it. The visuals are amazing and I've only just scratched the surface. The body high is excellent and very smooth, no jitters that I've notice or anyone I've shared this with. It may not give me any insights or spiritual awakenings, but if I we're really being honest, most of us I think are really after exactly what this chem offers." -- Exp 95033
[3750 ug, sublingual] "[T]he visuals were basically tangible. I could wave my hand in the air and felt as if I was playing with the energy surrounding me, it was absolute nirvana. I remember thinking to myself what a success the blotters had been, as I was laying in my bed in complete darkness staring at my hand, but having the best time of my life. A lot of the visuals consisted of infinite numbers of random shapes, all very reminiscent of the Matrix coding, just much more colorful and happy feeling. There were also massive amounts of trailing, I could wave my hand around in the air creating the most beautiful disturbances in the fields of energy all around me. It was like when you splash in the water and create all the ripples, except this was just air. Everything I would do in the world was just so beautiful, I thought to myself I couldn't believe I was surrounded by this beauty all day everyday, I just have to remind myself it's there even when I can't see it. I can't describe enough how interactive these visuals are, it's seriously unreal." -- Exp 93644
[1000 ug, sublingual] "I loved how easy the comedown was. When I layed down, I was expecting the constant chatter/closed eye visuals I usually get, but my thinking was clear and it was pretty easy for me to fall asleep." -- Exp 94200
[2 blotter hits, buccal, 2 lines, insufflated] "Wow! visuals are crazy and the music is intense, waves of 3D objects have taken over my living room and everything looks beautiful! [...] Amazing party drug! I don't feel very stimulated even though this is a psychedelic stimulant? But euphoria I feel quite allot and this is a really social drug although on high doses its a bit hard to have a real conversation." -- Exp 95008
[1 blotter hit, sublingual/buccal] "25I is probably the most stereotypical/recreational psychedelic drug I have ever used, and I've used quite a few psychedelics. 25I makes me feel good, I have insane visuals, and it doesn't disrupt with my language abilities (that much). It is almost nothing like 2C-I. Just because it has a 16x greater potency for the 5-HT2a receptor DOES NOT mean that this compound is just a 16x more potent version of 2C-I. In my opinion, 25I was more comparable to LSD/shrooms, than any phenethylamine I have used. However, despite its high recreational value, I do not consider this drug profound on the level of shrooms, Ayahuasca, or salvia." -- Exp 93884
[1500 ug, buccal] "CEV strong, really strong. Abrupt changes in ambient lighting cause rapid strobing. Strong erotic component to music, something in it and the feel of the rug and the sensation was really pushing me close to ecstasy a minute ago." -- Exp 93870
[1000 ug, insufflated] "There's a HEAVY sexual pull which I've yet to read about in other trip reports [...] I feel indescribable pleasure. Bliss. Nirvana. This is the ultimate human experience. My life up until this point has merely been preparation for this moment. Everything from here on afterwards will never be the same. I literally FEEL the beauty of the universe in its infinite complexity. My perception of myself is erased. There is no longer a 'me'. [...] This is one of the best if not THE BEST drug ever made. It would be almost impossible to improve. I am done searching for the perfect psychedelic; this is the one. Both low and high doses are extremely comfortable and get more rewarding as the dosage is pushed higher. Under its influence at relatively high doses there was no nausea, no anxiousness, and absolutely no fear." -- Exp 95009
[2000 ug, insufflated] "[T]he visuals totally absorbed my consciousness. Every moment would be "Oh my god! Why are there some many people roaming the woods?" or "SHIT, the ground is splitting open!". The path would seem to wind away into the sky or my friends would seem to be sucked into the ground. Everything including the trees, bushes, sky, and water would melt together to create one single image. [...] Almost every shadow I saw would turn into the image of a human, and artificial source of light would look like an eye. I started hearing people talk to me, feeling animals perch on my shoulder. Basically I just started hallucinating a bunch of things for no reason at all." -- Exp 92752
[1mg, buccal] "The closed eye visuals were calming, expansive, and beautiful. Many of the images reminded me of some drawings of animals by Native Americans. [...] As I sent it, memories of my childhood with her flashed through my mind, and I felt an enormous sadness thinking about how sad I imagine she felt when I left home for college. I cried for a good minute or two, and it felt wonderful." -- Exp 95147
[5 blotter hits, buccal] "My body felt like shit. I wasn't sure if I was going to shit or puke myself all over the couch or wherever I was. [...] In the meantime I could barely move, I felt like I had drank an entire bottle of vodka. But everything around me had gone to absolute crazy town. I mean, I completely lost sanity. There was no coherent theme, there was nothing to keep track of, everything just went absolutely fucking haywire bananas, there was no reality, just crazy morphing walls and images popping into and out of vision a bazillion times a second." -- Exp 94045
[1500 mcg, sublingual] "I saw rainbow prisms coming off of every object - similar to looking at a streetlight at night, but in broad daylight. I also had a significant "disco ball" effect - small spots of light on every surface." -- Exp 93624
Erowid's effects information is a summary of data gathered from users, research, and other resources. This information is intended to describe the range of effects people report experiencing. Effects may vary dramatically from one person to another or one experience to another based on a variety of factors such as body chemistry, age, gender, physical health, dose, form of material, etc.