Substance

Beilstein Registry Number 136380
Beilstein Preferred RN 94-59-7
CAS Registry Number 94-59-7
Chemical Name 5-allyl-benzo[1,3]dioxole

1-allyl-3,4-methylenedioxybenzene

safrole

4-allyl-1,2-(methylenedioxy)benzene

5-(2-propenyl)-1,3-benzodioxole
Autoname 5-allyl-benzo[1,3]dioxole
Molecular Formula C10H10O2
Molecular Weight 162.19
Lawson Number 21033
Compound Type heterocyclic
Constitution ID 120352
Tautomer ID 109325
Beilstein Reference 0-19-00-00039, 1-19-00-00617, 2-19-00-00029, 4-19-00-00275, 5-19-01-00553, 6-19
Entry Date 1988/06/27
Update Date 2002/04/29

Isolation from Natural Product 1 of 51

Isolation from Natural Product radix of Asiasarum heterotropoides var. mandshuricum (China)
Ref. 1 6188762; Journal; Takasaki, Midori; Konoshima, Takao; Yasuda, Ichiro; Hamano, Tomoko; Tokuda, Harukuni; BPBLEO; Biol.Pharm.Bull.; EN; 20; 7; 1997; 776 - 780.

Isolation from Natural Product 2 of 51

Isolation from Natural Product Ocotea pretiosa
Ref. 1 6159391; Journal; Araujo-Junior, Joao X. de; Barreiro, Eliezer J.; Parente, Jose P.; Fraga, Carlos A. M.; SYNCAV; Synth.Commun.; EN; 29; 2; 1999; 263 - 274.

Isolation from Natural Product 3 of 51

Isolation from Natural Product leaves of Piper aduncum
Ref. 1 6124808; Journal; Parmar, Virinder S.; Jain, Subhash C.; Gupta, Sangita; Talwar, Sangeeta; Rajwanshi, Vivek K.; et al.; PYTCAS; Phytochemistry; EN; 49; 4; 1998; 1069-1078.

Isolation from Natural Product 4 of 51

Isolation from Natural Product Piper aduncum
Ref. 1 6080863; Journal; Parmar, Virinder S.; Jain, Subhash C.; Bisht, Kirpal S.; Jain, Pajni; Taneja, Poonam; et al.; PYTCAS; Phytochemistry; EN; 46; 4; 1997; 597-674.

Isolation from Natural Product 5 of 51

Isolation from Natural Product Illicium dunnianum by extraction with CH2Cl2 in Soxhlet apparatus for 8 h, removal of solvent and chromatograophy
Ref. 1 6055384; Journal; Sy, Lai-King; Saunders, Richard M. K.; Brown, Geoffrey D.; PYTCAS; Phytochemistry; EN; 44; 6; 1997; 1099-1108.

Isolation from Natural Product 6 of 51

Isolation from Natural Product Piper auritum
Ref. 1 5884642; Journal; Nair, Muraleedharan G.; Sommerville, John; Burke, Basil A.; PYTCAS; Phytochemistry; EN; 28; 2; 1989; 654-655.

Isolation from Natural Product 7 of 51

Isolation from Natural Product lhe petrol extract of the leaves of Drimys winteri
Ref. 1 5818808; Journal; Sierra, Jorge R.; Lopez, Jose T.; Cortes, Manuel J.; PYTCAS; Phytochemistry; EN; 25; 1; 1986; 253-254.

Isolation from Natural Product 8 of 51

Isolation from Natural Product Clausena excavata
Ref. 1 5718667; Journal; Wu, Tian-Shung; Huang, Shiow-Chyn; Lai, Jeng-Shiow; Teng, Che-Ming; Ko, Feng-Nien; Kuoh, Chang-Sheng; PYTCAS; Phytochemistry; EN; 32; 2; 1993; 449-452.

Isolation from Natural Product 9 of 51

Isolation from Natural Product leaves of Illicum tashiroi MAXIM., collected on Iriomote Island (Japan)
Ref. 1 5668828; Journal; Yakushijin, Kenichi; Tohshima, Tomoko; Suzuki, Rika; Murata, Hiroyuki; Lu, Sheng-Ten; Furukawa, Hiroshi; CPBTAL; Chem.Pharm.Bull.; EN; 31; 8; 1983; 2879-2883.

Isolation from Natural Product 10 of 51

Isolation from Natural Product aus Anethum sowa KURZ
Ref. 1 3339630; Journal; Baslas; Baslas; RSARAQ; Riechst.Aromen; 22; 1972; 200,202.

Isolation from Natural Product 11 of 51

Isolation from Natural Product aus Anethum graveolens
Ref. 1 4298940; Journal; Baslas; Baslas; RSARAQ; Riechst.Aromen; 22; 1972; 155,156,158.

Isolation from Natural Product 12 of 51

Isolation from Natural Product aus Eugenia bracteata Roxb.
Ref. 1 3615219; Journal; Narasimha; Nigam; RSARAQ; Riechst.Aromen; 22; 1972; 231,236.

Isolation from Natural Product 13 of 51

Isolation from Natural Product aus Pogostemon plectranthoides (Desf.)
Ref. 1 3737643; Journal; Nigam; Ramaiah; RSARAQ; Riechst.Aromen; 22; 1972; 378,388.

Isolation from Natural Product 14 of 51

Isolation from Natural Product aus aether. Oel v. Saccopetalum tomentosum
Ref. 1 3339628; Journal; Ramaiah; Nigam; RSARAQ; Riechst.Aromen; 22; 1972; 71,74.

Isolation from Natural Product 15 of 51

Isolation from Natural Product aus Acorus gramineus
Ref. 1 3958347; Journal; Fujita et al.; YKKZAJ; Yakugaku Zasshi; 90; 1970; 1367,1371; Chem.Abstr.; 74; 34553; 1971.

Isolation from Natural Product 16 of 51

Isolation from Natural Product aus d. Blaettern v. Hamamelis virginiana L.
Ref. 1 3614964; Journal; Messerschmidt; ARZNAD; Arzneim.Forsch.; 18; 1968; 1618.

Isolation from Natural Product 17 of 51

Isolation from Natural Product aus Magnolia salicifolia
Ref. 1 3614687; Journal; Fujita; Fujita; CPBTAL; Chem.Pharm.Bull.; 20; 1972; 2251.

Isolation from Natural Product 18 of 51

Isolation from Natural Product Schinus weinmanniae folius
Ref. 1 3181171; Journal; Fester et al.; RFIQA6; Rev.Fac.Ing.Quim.Univ.Nac.Litoral; 28; 1959; 9; Chem.Abstr.; 55; 10809; 1961.

Isolation from Natural Product 19 of 51

Isolation from Natural Product ........... Oil aus Myristica fraga.s
Ref. 1 3271861; Journal; Bejnarowicz; Kirch; JPMSAE; J.Pharm.Sci.; 52; 1963; 988.

Isolation from Natural Product 20 of 51

Isolation from Natural Product aether. Oel aus Ocimum basilicum
Ref. 1 3831982; Journal; Hoerhammer et al.; JPMSAE; J.Pharm.Sci.; 53; 1964; 1033; Chem.Abstr.; 305; 1962.

Isolation from Natural Product 21 of 51

Isolation from Natural Product Petersiliensamenoel
Ref. 1 3219839; Journal; Dallacker et al.; MOCMB7; Monatsh.Chem.; 91; 1960; 1089,1096.

Isolation from Natural Product 22 of 51

Isolation from Natural Product aetherisches Oel von Eremopleila Longifolia F.Muell.
Ref. 1 3271836; Journal; Della; Jefferies; AJCHAS; Aust.J.Chem.; 14; 1961; 663.

Isolation from Natural Product 23 of 51

Isolation from Natural Product Bananenaromastoff, Gaschromat. Nachweis
Ref. 1 301089; Journal; Tressl,R. et al.; ZENBAX; Z.Naturforsch.B Anorg.Chem.Org.Chem.Biochem.Biophys.Biol.; GE; 24; 1969; 781-783.

Isolation from Natural Product 24 of 51

Isolation from Natural Product im Wurzelholz und in der Wurzelrinde von Sassafras officinalis Nees (Sassafraswurzeloel)
Note 1 Handbook
Ref. 1 500521; Journal; Power; Kleber; CHZEA6; Chem.Zentralbl.; GE; 68; II; 1897; 42.
Ref. 2 500511; Journal; Flueckiger; ANPYA2; Ann.Phys.(Leipzig); 158; 1876; 248.
Ref. 3 500494; Journal; Grimaux; Ruotte; BSCFAS; Bull.Soc.Chim.Fr.; <2> 11; 1869; 465; JLACBF; Justus Liebigs Ann. Chem.; 152; 1869; 91.
Ref. 4 500524; Journal; Saint-Evre; ANCPAC; Ann.Chim.(Paris); <3> 12; 1844; 107; JLACBF; Justus Liebigs Ann. Chem.; 52; 1844; 397.
Ref. 5 500525; Book Review / Secondary Ref.; Binder; Buchners Repertorium fuer die Pharmacie 11 <1821>, 346.

Isolation from Natural Product 25 of 51

Isolation from Natural Product als Hauptbestandteil des aether. Oels der Wurzel und des Wurzelstocks von Asarum arifolium
Note 1 Handbook
Ref. 1 500496; Journal; Miller; ARPMAS; Arch.Pharm.(Weinheim Ger.); 240; 1902; 377.

Isolation from Natural Product 26 of 51

Isolation from Natural Product im Oel aus den Blaettern und den gruenen Fruechten von Illicium religiosum (Japanisches Sternanisoel)
Note 1 Handbook
Ref. 1 500501; Journal; Eijkman; RTCPA3; Recl.Trav.Chim.Pays-Bas; 4; 1885; 39.
Ref. 2 1518772; Journal; Tardy; BSCFAS; Bull.Soc.Chim.Fr.; <3> 27; 1902; 995.

Isolation from Natural Product 27 of 51

Isolation from Natural Product im aether. Oel aus der Wurzelrinde von Cinnamomum ceylanicum
Note 1 Handbook
Ref. 1 500518; Journal; Pilgrim; CHZEA6; Chem.Zentralbl.; GE; 80; I; 1909; 534.

Isolation from Natural Product 28 of 51

Isolation from Natural Product im Campheroel (Cinnamomum Camphora)
Note 1 Handbook
Ref. 1 500517; Book Review / Secondary Ref.; Schimmel & Co.; Bericht vom September 1885, 7.

Isolation from Natural Product 29 of 51

Isolation from Natural Product im aether. Rindenoel von Cinnamomum pedatinervium
Note 1 Handbook
Ref. 1 500516; Journal; Goulding; JCSOA9; J.Chem.Soc.; 83; 1903; 1099.

Isolation from Natural Product 30 of 51

Isolation from Natural Product im Massoirindenoel (Cinnamomum, Spezies unsicher)
Note 1 Handbook
Ref. 1 500368; Journal; Woy; ARPMAS; Arch.Pharm.(Weinheim Ger.); 228; 1890; 40.

Isolation from Natural Product 31 of 51

Isolation from Natural Product im aether. Muskatnussoel (Ol. Nucis moschatae)
Note 1 Handbook
Ref. 1 1297408; Journal; Power; Salway; JCSOA9; J.Chem.Soc.; 91; 1907; 2045,2049.

Isolation from Natural Product 32 of 51

Isolation from Natural Product Vorkommen von Safrol in weiteren aetherischen Oelen
Note 1 Handbook
Ref. 1 500513; Book Review / Secondary Ref.; Semmler; Die aetherischen Oele, Bd. IV <Leipzig 1907>, S. 144ff.

Isolation from Natural Product 33 of 51

Isolation from Natural Product im californischen Lorbeerblaetteroel (von Umbellularia californica)
Note 1 Handbook
Ref. 1 500495; Journal; Power; Lees; JCSOA9; J.Chem.Soc.; 85; 1904; 638.

Isolation from Natural Product 34 of 51

Isolation from Natural Product Vorkommen im Oel der Fruechte von Illicium verum (Sternanisoel)
Note 1 Handbook
Ref. 1 504621; Journal; Schimmel & Co.; CHZEA6; Chem.Zentralbl.; GE; 81; I; 1910; 1719.

Isolation from Natural Product 35 of 51

Isolation from Natural Product Im aether. Oel der Blaetter von Atherosperma moschatum Labill.
Note 1 Handbook
Ref. 1 504620; Journal; Scott; JCSOA9; J.Chem.Soc.; 101; 1912; 1613.

Isolation from Natural Product 36 of 51

Isolation from Natural Product Im aether. Oel des Holzes von Cinnamomum glanduliferum Meissn.
Note 1 Handbook
Ref. 1 504619; Journal; Pickles; JCSOA9; J.Chem.Soc.; 101; 1912; 1437.

Isolation from Natural Product 37 of 51

Isolation from Natural Product Im aether. Oel der Rinde von Cinnamomum Oliveri Bail.
Note 1 Handbook
Ref. 1 504618; Journal; Hargreaves; JCSOA9; J.Chem.Soc.; 109; 1916; 751.

Isolation from Natural Product 38 of 51

Isolation from Natural Product Safrol ist der Hauptbestandteil des Oeles aus dem Holz von Cinnamomum Parthenoxylon Meissn.
Note 1 Handbook
Ref. 1 504617; Journal; Schimmel & Co.; CHZEA6; Chem.Zentralbl.; GE; 82; I; 1911; 1837.

Isolation from Natural Product 39 of 51

Isolation from Natural Product im aether. Oel aus den Blaettern von Doryphora Sassafras
Note 1 Handbook
Ref. 1 506411; Journal; Penfold; PEORAA; Perfum.Essent.Oil Rec.; 13; 273; CHZEA6; Chem.Zentralbl.; GE; 93; IV; 1922; 673.

Isolation from Natural Product 40 of 51

Isolation from Natural Product im Pichurimbohnen-Oel
Note 1 Handbook
Ref. 1 506410; Journal; Roure-Bertrand fils; CHZEA6; Chem.Zentralbl.; GE; 93; I; 1922; 360.

Isolation from Natural Product 41 of 51

Isolation from Natural Product bildet den Hauptbestandteil der aether. Oele aus der Rinde und den Blaettern von Laurelia serrata Bert.
Note 1 Handbook
Ref. 1 506408; Journal; Fester; Salgado; ANCEAD; Angew.Chem.; 42; 1929; 988.
Ref. 2 506409; Book Review / Secondary Ref.; Schimmel & Co.; Ber. Schimmel 1927, 61; C. 1927 II, 1518.

Isolation from Natural Product 42 of 51

Isolation from Natural Product Vorkommen in verschiedenen japanischen aetherischen Oelen
Note 1 Handbook
Ref. 1 506407; Journal; Anonymus; CHZEA6; Chem.Zentralbl.; GE; 91; III; 1920; 597.

Isolation from Natural Product 43 of 51

Isolation from Natural Product aus dem aetherischen Oel der Wurzeln von Asarum sieboldii
Note 1 Handbook
Ref. 1 542486; Journal; Kaku; Kondo; YKKZAJ; Yakugaku Zasshi; 51; 1931; 8, 16; dtsch. Ref. S. 3, 6; Chem.Abstr.; 1931; 1948.

Isolation from Natural Product 44 of 51

Isolation from Natural Product aus dem aetherischen Oel der Blaetter von Boronia pinnata
Note 1 Handbook
Ref. 1 542485; Journal; Penfold; JPRSA5; J.Proc.R.Soc.N.S.W.; 62; 1928; 225, 230.

Isolation from Natural Product 45 of 51

Isolation from Natural Product aus dem aetherischen Oel der Blaetter von Cinnamomum camphora
Note 1 Handbook
Ref. 1 1365400; Journal; Naito; NKAKB8; Nippon Kagaku Kaishi; 64; 1943; 1125; Chem.Abstr.; 1947; 3776.
Ref. 2 542484; Journal; Fujita; NKAKB8; Nippon Kagaku Kaishi; 63; 1942; 58, 62; Chem.Abstr.; 1947; 3509.

Isolation from Natural Product 46 of 51

Isolation from Natural Product aus dem aetherischen Oel der Blaetter von Cinnamomum micranthum
Note 1 Handbook
Ref. 1 542482; Journal; Fujita; Tamashita; NKAKB8; Nippon Kagaku Kaishi; 65; 1944; 385, 388, 591; Chem.Abstr.; 1947; 3509.

Isolation from Natural Product 47 of 51

Isolation from Natural Product aus dem aetherischen Oel der Blaetter von Illicium parviflorum
Note 1 Handbook
Ref. 1 542481; Journal; Foote; JPHAA3; J.Am.Pharm.Assoc.; 27; 1938; 573.

Isolation from Natural Product 48 of 51

Isolation from Natural Product aus dem aetherischen Oel der Wurzeln von Ligusticum acutilobum
Note 1 Handbook
Ref. 1 592320; Journal; Noguchi; Kawanami; YKKZAJ; Yakugaku Zasshi; 57; 1937; 783, 788; dtsch. Ref. S. 196, 199; CHZEA6; Chem.Zentralbl.; GE; 108; II; 1937; 4050.
Ref. 2 512471; Journal; Noguchi et al.; YKKZAJ; Yakugaku Zasshi; 57; 1937; 769, 773; dtsch. Ref. S. 187; Chem.Abstr.; 1938; 3360.

Isolation from Natural Product 49 of 51

Isolation from Natural Product aus dem aetherischen Oel der Rinde von Nemuaron humboldtii
Note 1 Handbook
Ref. 1 542478; Journal; Chabeau; Bl. Acad. Med. Belgique; <6> 3; 1938; 46, 52.

Isolation from Natural Product 50 of 51

Isolation from Natural Product aus dem aetherischen Oel des Holzes von Ocotea pretiosa
Note 1 Handbook
Ref. 1 542448; Journal; Hickey; JOCEAH; J.Org.Chem.; 13; 1948; 443, 445.
Ref. 2 542477; Journal; Raoul; Jachan; Rev. Quim. ind.; 19; 1950; 12, 13.

Isolation from Natural Product 51 of 51

Isolation from Natural Product aus dem aetherischen Oel des Holzes von Sassafras albidum
Note 1 Handbook
Ref. 1 542448; Journal; Hickey; JOCEAH; J.Org.Chem.; 13; 1948; 443, 445.