New Membership Gift--Ltd. Ed. Art Print
"Solve et Elucido" is a fantastic signed & numbered reverberating giclee print
available for a $500 level donation. It is 12" x 12", on canvas, signed
by the artist as well as Erowid founders Earth and Fire.

Erowid References Database

Stiglick A, Kalant H. 
“Residual effects of chronic cannabis treatment on behavior in mature rats”. 
Psychopharmacology (Berl). 1985;85(4):436-9.
Mature rats (starting weight at least 270 g) were treated daily with cannabis extract (daily THC dose 20 mg/kg) for 3 months. After a 1- to 4-month drug-free period, residual effects on a variety of behaviors were studied. No residual effects were found in learning of an eight-arm radial maze task, nor on a differential reinforcement of low-rate responding (DRL-20) task, nor on open field activity. On the other hand, two-way shuttle box avoidance learning was facilitated by previous cannabis treatment, since cannabis-treated rats exhibited shorter mean latencies to avoid footshock than vehicle controls. The findings indicate greater vulnerability of immature organisms (previous studies) than mature organisms (the present study) to long-term effects of chronic cannabis administration.
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