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Erowid References Database

Tomlinson A. 
Update in Anaesthesia. 1994;4.
Ketamine is frequently described as a "unique drug" because it has hypnotic (sleep producing), analgesic (pain relieving) and amnesic (short term memory loss) effects - no other drug used in clinical practice combines these three important features. It was first used clinically in 1970, and because of these combined effects it was thought that it might be the perfect anaesthetic agent. This is not quite the case, but its continued use in all parts of the world demonstrates that for certain situations, when used appropriately, it is a very valuable drug.

Ketamine is available in three different concentrations - 10mg/ml, 50 mg/ml and 100 mg/ml. The 10 mg/ml is for intravenous use; the 50 mg/ml and 100 mg/ml preparations are for intramuscular use. If only one strength is to be kept in a hospital, the 50 mg/ml ampoule is the best compromise as this may be diluted down to 10 mg/ml for intravenous injections.
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