Did you know that Erowid has a print publication?
Erowid Extracts is published twice a year for members.

Erowid References Database

Clements JA, Nimmo WS. 
“Pharmacokinetics and analgesic effect of ketamine in man”. 
Br J Anaesth. 1981 Jan;53(1):27-30.
Abstract
The pharmacokinetics and analgesic effect of i.v. ketamine in doses of 125 microgram kg-1 and 250 microgram kg-1 were determined in five healthy volunteers. Analgesia was measured with the submaximal effort tourniquet test. Both doses of ketamine prolonged the period of pain-free ischaemic exercise while the plasma ketamine concentration was greater than 100 ng ml-1. Ketamine was distributed rapidly (T 1/2 alpha = 17 min). The elimination half-life was 186 min.
Submit Comment
[ Cite HTML ]



Erowid.org Plants & Drugs Mind & Spirit Freedom & Law Arts & Sciences Search About Erowid and Feedback Library & Bookstore Copyrights Memberships noref