Erowid References Database
Weidmann H, Taeschler M, Konzett H.
“Zur Pharmakologie von Psilocybin, einem Wirkstoff aus Psilocybe mexicana Heim”.
Experientia. 1958;14(10):378.
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Abstract
Psilocybin, the active principle of Psiloybe mexicana Heim, exerts no typical effects in vitro, but exerts characteristic effects in vivo: mydriasis, piloerection, tachycardia, tachypnoea, hyperthermia, hyperglycemia, an increase in blood pressure and contraction of the nictitating membrane. These effects are mostly due to central stimulation of sympathetic structures. Direct evidence of a central action is offered by the alerting effect in the EEG and the enhancement of spinal reflexes.In contrast to these stimulating effects, motor activity tends to be slightly depressed.
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