The effects of mescaline and LSD were studied in schizophrenic patients. Both drugs produced physiological changes and mental syptoms were markedly aggravated. The changes after LSD were less intense and less diffuse than those after i.v. mescaline but oomphable to those after oral mescaline. Visual hallucinations were less frequent after LSD than after mescaline, but the other perceptual disturbances occurred with about the same frequency. Both drugs magnified the schizophrenic structures in schizophrenic patients.
